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Themed collection 2016 Journal of Materials Chemistry B Most Accessed Manuscripts

30 items
Highlight

Microneedle-based sensors for medical diagnosis

The field of microneedle sensors is reviewed discussing current trends and future applications.

Graphical abstract: Microneedle-based sensors for medical diagnosis
Review Article

Carbon dots: surface engineering and applications

Surface engineering of carbon dots and their applications in targeting sensing, accurate drug delivery and high resolution bioimaging are highlighted.

Graphical abstract: Carbon dots: surface engineering and applications
Open Access Review Article

Pluripotent stem cell derived hepatocytes: using materials to define cellular differentiation and tissue engineering

Pluripotent stem cell derived liver cells (hepatocytes) represent a promising alternative to primary tissue for biological and clinical applications.

Graphical abstract: Pluripotent stem cell derived hepatocytes: using materials to define cellular differentiation and tissue engineering
Review Article

Graphene scaffolds in progressive nanotechnology/stem cell-based tissue engineering of the nervous system

Graphene scaffolds are highly promising candidates in the versatile physicochemical stimulated proliferation/differentiation of neural stem cells required in future regenerative nanomedicine.

Graphical abstract: Graphene scaffolds in progressive nanotechnology/stem cell-based tissue engineering of the nervous system
Review Article

Micro/nanostructured surfaces for self-powered and multifunctional electronic skins

We introduce recent advances in the design of bioinspired micro/nanostructures and 2D/3D structures for the enhancement of energy harvesting and multifunctional sensing properties of flexible electronic skins.

Graphical abstract: Micro/nanostructured surfaces for self-powered and multifunctional electronic skins
Review Article

Nanostructure-based surface-enhanced Raman scattering biosensors for nucleic acids and proteins

Nanostructure-based SERS platforms have been developed for nucleic acid and protein detection ranging from label-free, labeled and multiplex analyses.

Graphical abstract: Nanostructure-based surface-enhanced Raman scattering biosensors for nucleic acids and proteins
Review Article

Biomolecular strategies to modulate the macrophage response to implanted materials

Materials engineered to display immunomodulatory molecules including adhesion ligands, cytokines, and self-proteins, target receptors on immune cells to modulate their response to biomaterial implants.

Graphical abstract: Biomolecular strategies to modulate the macrophage response to implanted materials
Review Article

PEG based anti-cancer drug conjugated prodrug micelles for the delivery of anti-cancer agents

Development of polymer prodrug conjugates has evolved recently in the nano-medicine field for cancer diagnosis and treatment. This review focuses on the development of different types of PEG based polymer drug conjugates used for the delivery of anti-cancer agents.

Graphical abstract: PEG based anti-cancer drug conjugated prodrug micelles for the delivery of anti-cancer agents
Review Article

Cellular modulation by the elasticity of biomaterials

The elasticity of the extracellular matrix has been increasingly recognized as a dominating factor of cell fate and activities. This review provides an overview of the general principles and recent advances in the field of matrix elasticity-dependent regulation of a variety of cellular activities and functions, the underlying biomechanical and molecular mechanisms, as well as the pathophysiological implications.

Graphical abstract: Cellular modulation by the elasticity of biomaterials
Communication

Enhanced user-control of small molecule drug release from a poly(ethylene glycol) hydrogel via azobenzene/cyclodextrin complex tethers

Photoresponsive azobenzene–cyclodextrin guest–host chemistry can be used to control the release rate of a small peptide from a PEG hydrogel with light.

Graphical abstract: Enhanced user-control of small molecule drug release from a poly(ethylene glycol) hydrogel via azobenzene/cyclodextrin complex tethers
Communication

A facile and one-step ethanol-thermal synthesis of MoS2 quantum dots for two-photon fluorescence imaging

MoS2 quantum dots with two-photon fluorescence features are synthesized through a one-step solvothermal approach and successfully used for cellular bioimaging.

Graphical abstract: A facile and one-step ethanol-thermal synthesis of MoS2 quantum dots for two-photon fluorescence imaging
Paper

Carbon dots as a trackable drug delivery carrier for localized cancer therapy in vivo

Green carbon dots with a carboxyl-rich surface were employed as a selective nanocarrier for fluorescent traceable and pH-sensitive Doxorubicin delivery in localized cancer treatment.

Graphical abstract: Carbon dots as a trackable drug delivery carrier for localized cancer therapy in vivo
Paper

Preparation of graphene nano-sheet bonded PDA/MOF microcapsules with immobilized glucose oxidase as a mimetic multi-enzyme system for electrochemical sensing of glucose

A novel amperometric biosensor for glucose detection was fabricated based on a mimetic multi-enzyme system by combing mimetic enzymes (metal–organic frameworks, MOFs) and glucose oxidase (GOx).

Graphical abstract: Preparation of graphene nano-sheet bonded PDA/MOF microcapsules with immobilized glucose oxidase as a mimetic multi-enzyme system for electrochemical sensing of glucose
Paper

Silica-assisted incorporation of polydopamine into the framework of porous nanocarriers by a facile one-pot synthesis

Mussel-inspired polydopamine (PDA), with its advanced bio-adhesive properties, has shown great potential in drug delivery based on host–guest interaction.

Graphical abstract: Silica-assisted incorporation of polydopamine into the framework of porous nanocarriers by a facile one-pot synthesis
Paper

Multicolour fluorescent carbon nanoparticle probes for live cell imaging and dual palladium and mercury sensors

Cytocompatible carbon nanoparticles (CNPs) having high quantum yield and multicolour bioimaging properties were synthesized and employed as sensitive, selective and rapid dual sensor for Pd2+ and Hg2+.

Graphical abstract: Multicolour fluorescent carbon nanoparticle probes for live cell imaging and dual palladium and mercury sensors
Paper

Reduction-responsive fluorescence off–on BODIPY–camptothecin conjugates for self-reporting drug release

A reduction-responsive fluorescence off–on theranostic prodrug with self-reporting drug release was constructed based on boron dipyrromethene (BODIPY) and therapeutic drug camptothecin (CPT) with a long flexible disulfide linker.

Graphical abstract: Reduction-responsive fluorescence off–on BODIPY–camptothecin conjugates for self-reporting drug release
Paper

Gelatin methacrylate/carboxybetaine methacrylate hydrogels with tunable crosslinking for controlled drug release

In this work, methacrylated gelatin (GelMA) based hydrogels were fabricated with carboxybetaine methacrylate (CBMA) to manipulate the properties of the gelatin-based hydrogels, since CBMA is a much smaller compound compared to gelatin.

Graphical abstract: Gelatin methacrylate/carboxybetaine methacrylate hydrogels with tunable crosslinking for controlled drug release
Open Access Paper

A switchable peroxidase mimic derived from the reversible co-assembly of cytochrome c and carbon dots

We describe a straightforward tactic to boost the inherently low peroxidase-like activity of the heme-protein equine cytochrome c following its electrostatic assembly onto the carbon nanodot surface.

Graphical abstract: A switchable peroxidase mimic derived from the reversible co-assembly of cytochrome c and carbon dots
Paper

Bio-inspired smart hydrogel with temperature-dependent properties and enhanced cell attachment

Stimuli-responsive smart hydrogels have been exploited for various applications, including as biomaterials with environment-dependent changes in hydrophobicity, stiffness or volume.

Graphical abstract: Bio-inspired smart hydrogel with temperature-dependent properties and enhanced cell attachment
Paper

Biomimetic gelatin methacrylamide hydrogel scaffolds for bone tissue engineering

The biomimetic GelMA scaffolds which have highly porous, interconnected macropores, and rough surface could promote ADSC to differentiate into osteoblasts and bone formation.

Graphical abstract: Biomimetic gelatin methacrylamide hydrogel scaffolds for bone tissue engineering
Open Access Paper

Novel magneto-responsive membrane for remote control switchable molecular sieving

Magneto-responsive separation membrane: reversible change of molecule sieving through pore-confined polymeric hydrogel network by remote control of immobilized “nano heaters” with alternating magnetic field.

Graphical abstract: Novel magneto-responsive membrane for remote control switchable molecular sieving
Paper

A toolbox for controlling the properties and functionalisation of hydrazone-based supramolecular hydrogels

In situ multicomponent hydrogelator formation enables straightforward chemical functionalisation of supramolecular hydrogels.

Graphical abstract: A toolbox for controlling the properties and functionalisation of hydrazone-based supramolecular hydrogels
Paper

A self-healing, re-moldable and biocompatible crosslinked polysiloxane elastomer

The self-healable polysiloxane elastomers cross-linked with DA bonds show high healing efficiency, good mechanical properties and good biocompatibility.

Graphical abstract: A self-healing, re-moldable and biocompatible crosslinked polysiloxane elastomer
Paper

Electrospun polyurethane/keratin/AgNP biocomposite mats for biocompatible and antibacterial wound dressings

Keratin based biomaterials have emerged as potential candidates for various biomedical and biotechnological applications due to their intrinsic biocompatibility, biodegradability, mechanical durability, and natural abundance.

Graphical abstract: Electrospun polyurethane/keratin/AgNP biocomposite mats for biocompatible and antibacterial wound dressings
Open Access Paper

High biocompatibility and improved osteogenic potential of amorphous calcium carbonate/vaterite

Metastable amorphous calcium carbonate (ACC), formed as a precursor of crystalline carbonated apatite/hydroxyapatite in human bone, can be stabilized by inorganic polyphosphate. The resulting CaCO3/polyP, containing small amounts of vaterite, has osteogenic potential and potential application as a scaffold material for bone implants.

Graphical abstract: High biocompatibility and improved osteogenic potential of amorphous calcium carbonate/vaterite
Paper

Green preparation of nitrogen-doped carbon dots derived from silkworm chrysalis for cell imaging

Carbon dots (CDs) with a high quantum yield of 46% are prepared using a green one-pot approach under microwaves with silkworm chrysalis which has been used for cell imaging.

Graphical abstract: Green preparation of nitrogen-doped carbon dots derived from silkworm chrysalis for cell imaging
Open Access Paper

Direct exfoliation of graphite into graphene in aqueous solutions of amphiphilic peptides

Peptide-mediated solution phase graphene exfoliation.

Graphical abstract: Direct exfoliation of graphite into graphene in aqueous solutions of amphiphilic peptides
Paper

Prussian blue nanoparticles encapsulated inside a metal–organic framework via in situ growth as promising peroxidase mimetics for enzyme inhibitor screening

Metal–organic framework-based peroxidase mimetics for enzyme-inhibitor screening.

Graphical abstract: Prussian blue nanoparticles encapsulated inside a metal–organic framework via in situ growth as promising peroxidase mimetics for enzyme inhibitor screening
Paper

Protein-modified hollow copper sulfide nanoparticles carrying indocyanine green for photothermal and photodynamic therapy

Protein-modified hollow copper sulfide nanoparticles carrying indocyanine green (ICG) facilitate combined therapeutic effects including photothermal therapy of CuS nanocarriers and cytotoxic effects of photodynamic and photothermal therapy by ICG.

Graphical abstract: Protein-modified hollow copper sulfide nanoparticles carrying indocyanine green for photothermal and photodynamic therapy
Paper

Dual-targeted activatable photosensitizers with aggregation-induced emission (AIE) characteristics for image-guided photodynamic cancer cell ablation

The currently available photosensitizers (PSs) for photodynamic therapy (PDT) can easily lead to undesirable normal cell death due to their intrinsic photo-toxicity and lack of selectivity for cancer cells.

Graphical abstract: Dual-targeted activatable photosensitizers with aggregation-induced emission (AIE) characteristics for image-guided photodynamic cancer cell ablation
30 items

About this collection

This web collection features the top 30 most downloaded articles published in Journal of Materials Chemistry B in 2016. 

Congratulations to all of the authors whose articles have been featured!

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