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Themed collection Lab on a Chip: Insights Issue

18 items
Editorial

The lab finally comes to the chip!

George Whitesides, the Chair of the Editorial Board of Lab on a Chip, introduces this year’s “Insights” themed issue.

Graphical abstract: The lab finally comes to the chip!
From the themed collection: Lab on a Chip: Insights Issue
Open Access Frontier

User-friendly 3D bioassays with cell-containing hydrogel modules: narrowing the gap between microfluidic bioassays and clinical end-users' needs

This frontier article reviews recent progress in the development and application of user-friendly 3D bioassay techniques combined with cell-containing hydrogel modules.

Graphical abstract: User-friendly 3D bioassays with cell-containing hydrogel modules: narrowing the gap between microfluidic bioassays and clinical end-users' needs
From the themed collection: Lab on a Chip: Insights Issue
Frontier

Physics and technological aspects of nanofluidics

Cartoon representing the main mechanisms that operate in the nano-, micro- and millifluidic realms. The mechanisms are illustrated by characters whose positions in the spectrum of scales are fixed by the characteristic lengths they are associated with. The fundamental questions of nanofluidics are the following: How do the characteristic scales pertaining to the 1–100 nm range interfere with the system size? Can they combine together to produce new physical effects?

Graphical abstract: Physics and technological aspects of nanofluidics
From the themed collection: Lab on a Chip: Insights Issue
Frontier

Gradient generation platforms: new directions for an established microfluidic technology

Microscale platforms are enabling for cell-based studies as they allow the recapitulation of physiological conditions such as extracellular matrix (ECM) configurations and soluble factors interactions.

Graphical abstract: Gradient generation platforms: new directions for an established microfluidic technology
From the themed collection: Lab on a Chip: Insights Issue
Open Access Frontier

Nanocrystal synthesis in microfluidic reactors: where next?

The authors contemplate the challenges ahead for nanocrystal synthesis in microreactors.

Graphical abstract: Nanocrystal synthesis in microfluidic reactors: where next?
From the themed collection: Lab on a Chip: Insights Issue
Open Access Frontier

Digital biology and chemistry

A personal overview of digital biology and chemistry in the context of lab-on-a-chip technologies.

Graphical abstract: Digital biology and chemistry
From the themed collection: Lab on a Chip: Insights Issue
Open Access Frontier

Tools for chemical synthesis in microsystems

Major developments in systems for flow chemistry are reviewed and limitations underlying the development of chip-scale integrated systems are discussed.

Graphical abstract: Tools for chemical synthesis in microsystems
From the themed collection: Lab on a Chip: Insights Issue
Open Access Frontier

Nanofluidics in point of care applications

The use of liquid flow around or in structures of smaller than 100 nm in point of care applications.

Graphical abstract: Nanofluidics in point of care applications
From the themed collection: Lab on a Chip: Insights Issue
Frontier

Approaching the in vitro clinical trial: engineering organs on chips

In vitro cell culture and animal models are the most heavily relied upon tools of the pharmaceutical industry.

Graphical abstract: Approaching the in vitro clinical trial: engineering organs on chips
From the themed collection: Lab on a Chip: Insights Issue
Frontier

Insight: implantable medical devices

This perspective article provides an overview of the implantable medical device ecosystem, highlights recent developments, and discusses challenges and opportunities for translation of new innovative implants enabled by microtechnologies and microfabrication.

Graphical abstract: Insight: implantable medical devices
From the themed collection: Implantable Devices
Frontier

Protein measurements in microwells

Protein measurements are essential to many fields ranging from fundamental biochemistry to clinical diagnostics.

Graphical abstract: Protein measurements in microwells
From the themed collection: Lab on a Chip: Insights Issue
Frontier

Energy: the microfluidic frontier

Highlighted here are the exceptional opportunities I see for microfluidics in energy.

Graphical abstract: Energy: the microfluidic frontier
From the themed collection: Lab on a Chip: Insights Issue
Frontier

Lights and shadows on Food Microfluidics

Food Microfluidics: science, technology and creativity making food analysis safer, faster and easier.

Graphical abstract: Lights and shadows on Food Microfluidics
From the themed collection: Lab on a Chip: Insights Issue
Frontier

Microfluidics for single-cell genetic analysis

New tools are needed to study single-cell genetics, and a microfluidic approach offers unique advantages and challenges.

Graphical abstract: Microfluidics for single-cell genetic analysis
From the themed collection: Lab on a Chip: Insights Issue
Frontier

Smartphone technology can be transformative to the deployment of lab-on-chip diagnostics

The rapid expansion of mobile technology is transforming the biomedical landscape.

Graphical abstract: Smartphone technology can be transformative to the deployment of lab-on-chip diagnostics
From the themed collection: Lab on a Chip: Insights Issue
Frontier

Elevating sampling

This perspective highlights challenges and opportunities in the collection and preparation of a target from real-world sources for subsequent processing in micro- and nanofluidic systems.

Graphical abstract: Elevating sampling
From the themed collection: Lab on a Chip: Insights Issue
Frontier

Mobile phones democratize and cultivate next-generation imaging, diagnostics and measurement tools

Some of the emerging applications and the future opportunities and challenges created by the use of mobile phones and their embedded components for the development of next-generation imaging, sensing, diagnostics and measurement tools are discussed.

Graphical abstract: Mobile phones democratize and cultivate next-generation imaging, diagnostics and measurement tools
From the themed collection: Lab on a Chip: Recent Review Articles
Critical Review

Biomedical imaging and sensing using flatbed scanners

In this Review, we provide an overview of flatbed scanner based biomedical imaging and sensing techniques.

Graphical abstract: Biomedical imaging and sensing using flatbed scanners
From the themed collection: Lab on a Chip: Insights Issue
18 items

About this collection

Lab on a Chip constantly strives to assist and stimulate the community to develop new tools and concepts for advancement and adaptation of microfluidics in any way that the journal is able. Guest edited by Professor George Whitesides, Chair of the Lab on a Chip Editorial Board, this collection of articles features insightful and unique articles focusing on the potential for microfluidics in today’s society. Covering topics of mobile diagnostics, implantable medical devices, smartphone technology, food microfluidics, digital biology and more, this issue collates the opinions and views of thought leaders in the field, who communicate their aspirations and concerns for the subject, based on their own experiences.

Spotlight

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