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Access to sulfonylated furans or imidazo[1,2-a]pyridines via a metal-free three-component, domino reaction

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Abstract

An efficient three-component reaction of 1,3-dicarbonyl compounds or pyridin-2-amines with ynals and sodium benzenesulfinates has been developed. This domino process provides a new and effective strategy for the preparation of sulfonylated furan or imidazo[1,2-a]pyridine derivatives. The strategy exhibits excellent functional group tolerance and good efficiency.

Graphical abstract: Access to sulfonylated furans or imidazo[1,2-a]pyridines via a metal-free three-component, domino reaction

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Publication details

The article was received on 02 May 2018, accepted on 13 Jun 2018 and first published on 14 Jun 2018


Article type: Research Article
DOI: 10.1039/C8QO00443A
Citation: Org. Chem. Front., 2018, Advance Article
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    Access to sulfonylated furans or imidazo[1,2-a]pyridines via a metal-free three-component, domino reaction

    Z. Cui, B. Zhu, X. Li and H. Cao, Org. Chem. Front., 2018, Advance Article , DOI: 10.1039/C8QO00443A

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