Jump to main content
Jump to site search

Issue 14, 2018
Previous Article Next Article

Visible light-induced aryltrifluoromethylation of hydroxy alkenes via radical trifluoromethylation-triggered aryl and heteroaryl migration

Author affiliations

Abstract

An efficient protocol was developed to achieve the aryltrifluoroalkylation of hydroxy alkenes via radical trifluoromethylation-triggered aryl migration. This method possesses several interesting features: (I) visible light is used as the sole promoter; (II) a new version of Umemoto's reagent [2,8-difluoro-S-(trifluoromethyl)dibenzothiophenium triflate], which is stable, cheap and recyclable, serves as the CF3 source; (III) the aryl migration is chemoselective; (IV) structurally diverse trifluoromethyl ketones can be produced.

Graphical abstract: Visible light-induced aryltrifluoromethylation of hydroxy alkenes via radical trifluoromethylation-triggered aryl and heteroaryl migration

Back to tab navigation

Supplementary files

Publication details

The article was received on 28 Apr 2018, accepted on 14 Jun 2018 and first published on 15 Jun 2018


Article type: Research Article
DOI: 10.1039/C8QO00430G
Citation: Org. Chem. Front., 2018,5, 2224-2228
  •   Request permissions

    Visible light-induced aryltrifluoromethylation of hydroxy alkenes via radical trifluoromethylation-triggered aryl and heteroaryl migration

    H. Wang, Q. Xu and S. Yu, Org. Chem. Front., 2018, 5, 2224
    DOI: 10.1039/C8QO00430G

Search articles by author

Spotlight

Advertisements