Issue 1, 2018

Expanding the structural analysis capabilities on an Orbitrap-based mass spectrometer for large macromolecular complexes

Abstract

Native mass spectrometry can provide insight into the structure of macromolecular biological systems. As analytes under investigation get larger and more complex, instrument capabilities need to be advanced. Herein, modifications to an Orbitrap Q Exactive Plus mass spectrometer that increase signal intensity, mass resolution, and maximum m/z measurable are described.

Graphical abstract: Expanding the structural analysis capabilities on an Orbitrap-based mass spectrometer for large macromolecular complexes

Supplementary files

Article information

Article type
Communication
Submitted
02 10月 2017
Accepted
08 11月 2017
First published
08 11月 2017

Analyst, 2018,143, 100-105

Expanding the structural analysis capabilities on an Orbitrap-based mass spectrometer for large macromolecular complexes

K. L. Fort, M. van de Waterbeemd, D. Boll, M. Reinhardt-Szyba, M. E. Belov, E. Sasaki, R. Zschoche, D. Hilvert, A. A. Makarov and A. J. R. Heck, Analyst, 2018, 143, 100 DOI: 10.1039/C7AN01629H

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements