Issue 25, 2015

Ethanol induces the formation of water-permeable defects in model bilayers of skin lipids

Abstract

We show that ethanol can induce the formation of water-permeable defects in model membranes of skin, providing a fresh perspective on ethanol as a membrane modulator. We rationalise our findings in terms of the chemical nature of ethanol, i.e., a combination of its hydrogen bonding propensity and amphiphilic character.

Graphical abstract: Ethanol induces the formation of water-permeable defects in model bilayers of skin lipids

Supplementary files

Article information

Article type
Communication
Submitted
28 ⴽⵜⵓ 2014
Accepted
23 ⴷⵓⵊ 2014
First published
23 ⴷⵓⵊ 2014

Chem. Commun., 2015,51, 5406-5409

Author version available

Ethanol induces the formation of water-permeable defects in model bilayers of skin lipids

R. Thind, D. W. O'Neill, A. Del Regno and R. Notman, Chem. Commun., 2015, 51, 5406 DOI: 10.1039/C4CC08527B

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