Themed collection Nanoscale and Nanoscale Horizons: Surface Enhanced Raman Spectroscopy
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Unveiling brain disorders using liquid biopsy and Raman spectroscopy
Brain disorders, including neurodegenerative diseases (NDs) and traumatic brain injury (TBI), present significant challenges in early diagnosis and intervention.
Nanoscale, 2024,16, 11879-11913
https://doi.org/10.1039/D4NR01413H
![Open Access](https://www.rsc-cdn.org/pubs-core/2022.0.153/content/NewImages/open-access-icon-orange.png)
‘When is a hotspot a good nanospot’ – review of analytical and hotspot-dominated surface enhanced Raman spectroscopy nanoplatforms
Substrate development in surface-enhanced Raman spectroscopy (SERS) continues to attract research interest.
Nanoscale, 2024,16, 3293-3323
https://doi.org/10.1039/D3NR05332F
Material design, development, and trend for surface-enhanced Raman scattering substrates
Design, development and trend for SERS-active nanomaterials from single component to multi-components are comprehensively introduced, benefiting to the complete understanding of their research status and arousing the research enthusiasm on them.
Nanoscale, 2023,15, 10860-10881
https://doi.org/10.1039/D3NR01456H
Emerging SERS biosensors for the analysis of cells and extracellular vesicles
This article reviews the fundamentals of surface-enhanced Raman scattering (SERS) and nanomaterials that have been used to design SERS biosensors for the analysis of surface biomarkers on cells and extracellular vesicles.
Nanoscale, 2022,14, 15242-15268
https://doi.org/10.1039/D2NR03005E
Towards multi-molecular surface-enhanced infrared absorption using metal plasmonics
Surface-enhanced infrared absorption (SEIRA) leads to improved detection of polar molecules. Engineering of plasmonic substrates and combination with surface-enhanced Raman scattering (SERS) leads to multi-resonant detection and enhanced sensing.
Nanoscale Horiz., 2022,7, 1259-1278
https://doi.org/10.1039/D2NH00276K
Giant enhancement of the initial SERS activity for plasmonic nanostructures via pyroelectric PMN-PT
This paper presents a pyroelectric PMN-PT composite plasmonic Ag NP SERS substrate, whose initial SERS signal is further greatly enhanced under the action of a pyroelectric potential, with a dominant chemical mechanism.
Nanoscale Horiz., 2023,8, 948-957
https://doi.org/10.1039/D3NH00053B
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Coupling of plasmonic hot spots with shurikens for superchiral SERS-based enantiomer recognition
We suggest surface-enhanced Raman spectroscopy sensor based on chiral shurikens coupled with an array of Ag clusters, which can generate near-chiral plasmonic field using linearly polarized light to enantioselective enhance organic molecules.
Nanoscale Horiz., 2023,8, 499-508
https://doi.org/10.1039/D3NH00008G
Bimetallic alloy Ag@Au nanorings with hollow dual-rims focus near-field on circular intra-nanogaps
Here, we report a highly sensitive and reliable surface enhanced Raman scattering (SERS)-based immunoassay using bimetallic alloy Ag@Au hollow dual-rim nanorings (DRNs) where circular intra-nanogaps strongly collect an electromagnetic near-field.
Nanoscale Horiz., 2023,8, 185-194
https://doi.org/10.1039/D2NH00529H
High-specificity molecular sensing on an individual whispering-gallery-mode cavity: coupling-enhanced Raman scattering by photoinduced charge transfer and cavity effects
This work proposes an ultrasensitive and high-specificity whispering-gallery-mode (WGM) sensing method, which combines the light-matter interaction enhancement on a WGM cavity and the “fingerprint spectrum” of surface-enhanced Raman scattering.
Nanoscale Horiz., 2023,8, 195-201
https://doi.org/10.1039/D2NH00450J
Monitoring hydrogen transport through graphene by in situ surface-enhanced Raman spectroscopy
A surface-enhanced Raman spectroscopy-based in situ analytical tool for the sensitive and rapid monitoring of hydrogen transport through graphene was developed.
Nanoscale, 2023,15, 1537-1541
https://doi.org/10.1039/D2NR06010H
![Open Access](https://www.rsc-cdn.org/pubs-core/2022.0.153/content/NewImages/open-access-icon-orange.png)
Multiplexed molecular imaging with surface enhanced resonance Raman scattering nanoprobes reveals immunotherapy response in mice via multichannel image segmentation
Multiplexed imaging of 8 molecular targets with SERS nanoprobes in mice reveals spatially heterogeneous tumor responses to immunotherapy. Multichannel image segmentation enables classification of the tumor regions into responders and naïve.
Nanoscale Horiz., 2022,7, 1540-1552
https://doi.org/10.1039/D2NH00331G
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Salt-mediated, plasmonic field-field/field-lattice coupling-enhanced NIR-II photodynamic therapy using core-gap-shell gold nanopeanuts
It is demonstrated that filling salt in the nanogaps in core-gap-shell Au@gap@AuAg nanopeanuts can enhance their extinction coefficient in the 1000–1300 nm NIR-II region, singlet O2 sensitization QY, and NIR-II PDT efficacy for destroying tumors.
Nanoscale Horiz., 2022,7, 589-606
https://doi.org/10.1039/D1NH00631B
Etched-spiky Au@Ag plasmonic-superstructure monolayer films for triple amplification of surface-enhanced Raman scattering signals
The triple signal amplification for the SERS detection based on 2D monolayer film of etched spiky Au@Ag NPs.
Nanoscale Horiz., 2022,7, 554-561
https://doi.org/10.1039/D2NH00023G
![Open Access](https://www.rsc-cdn.org/pubs-core/2022.0.153/content/NewImages/open-access-icon-orange.png)
Gold nanoplasmonic particles in tunable porous silicon 3D scaffolds for ultra-low concentration detection by SERS
A new 3D composite substrate for on-chip surface enhanced Raman spectroscopy made of nanoporous silicon with embedded gold plasmonic nanoparticles – demonstration of 109 enhancement factor.
Nanoscale Horiz., 2021,6, 781-790
https://doi.org/10.1039/D1NH00228G
Origin of layer-dependent SERS tunability in 2D transition metal dichalcogenides
Exploring the influence of interlayer interaction on SERS performance by using 2D PtSe2 and ReS2 with different numbers of layers as the research objects.
Nanoscale Horiz., 2021,6, 186-191
https://doi.org/10.1039/D0NH00625D
Deformation induced evolution of plasmonic responses in polymer grafted nanoparticle thin films
Deformation induced modification of SERS response in polymer grafted plasmonic nanoparticle thin films yields insights into structure-function relationships in plasmonic networks.
Nanoscale, 2024,16, 11705-11715
https://doi.org/10.1039/D4NR00789A
Imaging of intracellular protein aggregates through plasmon-assisted clusteroluminescence
The formation of clusters in non-aromatic molecules can give rise to unconventional luminescence or clusteroluminescence.
Nanoscale, 2024,16, 11749-11761
https://doi.org/10.1039/D4NR01803F
Thermal-effect dominated plasmonic catalysis on silver nanoislands
The temperature-dependent in situ SERS spectra of 4-NTP and 4-ATP are investigated by designing a simple and effective self-assembly system with plasmonic nanoislands to explore the role of thermal effects on plasmon-induced catalytic reactions.
Nanoscale, 2024,16, 10745-10750
https://doi.org/10.1039/D4NR00049H
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Alternative nano-lithographic tools for shell-isolated nanoparticle enhanced Raman spectroscopy substrates
This work shows increased stability and homogeneity for shell-isolated nanoparticle enhanced Raman spectroscopy substrates fabricated by using a combination of lithography and atomic layer deposition, compared to chemically synthesized substrates.
Nanoscale, 2024,16, 7582-7593
https://doi.org/10.1039/D4NR00428K
![Open Access](https://www.rsc-cdn.org/pubs-core/2022.0.153/content/NewImages/open-access-icon-orange.png)
Plasmon resonance dynamics and enhancement effects in tris(2,2′-bipyridine)ruthenium(II) gold nanosphere oligomers
We report a plasmon-mediated resonance energy transfer in an optimized gold nanosphere oligomer system that enhances the photoexcited population of the well known Ru-dye, [Ru(BPY)3]2+ with a defluorescenced Raman signal.
Nanoscale, 2024,16, 5601-5612
https://doi.org/10.1039/D3NR06129A
![Open Access](https://www.rsc-cdn.org/pubs-core/2022.0.153/content/NewImages/open-access-icon-orange.png)
Strongly coupled plasmonic metal nanoparticles with reversible pH-responsiveness and highly reproducible SERS in solution
We report a facile method to prepare polymer-grafted plasmonic metal nanoparticles (NPs) that exhibit pH-responsive surface-enhanced Raman scattering (SERS).
Nanoscale, 2024,16, 708-718
https://doi.org/10.1039/D3NR05071H
Early-stage oral cancer diagnosis by artificial intelligence-based SERS using Ag NWs@ZIF core–shell nanochains
Surface-enhanced Raman spectroscopy (SERS) has great potential in early diagnosis of diseases by detecting volatile biomarkers in exhaled breath, for its high sensitivity, rich chemical molecular fingerprint information, and immunity to humidity.
Nanoscale, 2023,15, 13466-13472
https://doi.org/10.1039/D3NR02662K
Nanozymatic magnetic nanomotors for enhancing photothermal therapy and targeting intracellular SERS sensing
By making full use of magnetic gold nanocomposite intrinsic properties, a nanozymatic magnetic nanomotor is proposed to improve the effects of photothermal treatment and SERS sensing, realizing the integration of dual driving mechanisms and dual biomedical functions on one nanomotor.
Nanoscale, 2023,15, 12944-12953
https://doi.org/10.1039/D3NR02739B
Two-dimensional MBenes with ordered metal vacancies for surface-enhanced Raman scattering
A totally new SERS technology, MBene-enhanced Raman scattering, is developed by employing MBene as a SERS-active material. An ordered vacancy-triggered highly sensitive MBene-based SERS platform with superior signal uniformity is designed.
Nanoscale, 2023,15, 2779-2787
https://doi.org/10.1039/D2NR06280A
Nanosupernova: a new anisotropic nanostructure for SERS
We develop a simple synthesis method that results in the formation of quasi-spherical SERS nanotags and larger highly anisotropic nanoparticles with a novel structure, which we have designated nanosupernova.
Nanoscale, 2023,15, 2087-2095
https://doi.org/10.1039/D2NR05287C
Differentiation and classification of bacterial endotoxins based on surface enhanced Raman scattering and advanced machine learning
A rapid and simple method was proposed for differentiation and classification of eleven bacterial endotoxins based on surface enhanced Raman scattering (SERS) and advanced machine learning algorithms.
Nanoscale, 2022,14, 8806-8817
https://doi.org/10.1039/D2NR01277D
Quantitative assessment of in vivo distribution of nanoplastics in bivalve Ruditapes philippinarum using reliable SERS tag-labeled nanoplastic models
SERS tag-labeled nanoplastic models for quantitative analysis of nanoplastics (NPs) were developed and they suggested the risk of NP uptake by humans via bivalve seafood diets.
Nanoscale, 2022,14, 7807-7816
https://doi.org/10.1039/D2NR00157H
Assembly of gold nanorods functionalized by zirconium-based metal–organic frameworks for surface enhanced Raman scattering
Assembly of gold nanorods functionalized by zirconium-based metal–organic frameworks (Au nanorod@Zr-MOF) for superior SERS detection.
Nanoscale, 2022,14, 5561-5568
https://doi.org/10.1039/D2NR00298A
Anisotropic silica coating on gold nanorods boosts their potential as SERS sensors
Coating gold nanorods with mesoporous silica selectively at the tips boosts their ability to produce a SERS signal with methylene blue compared to coating with a complete shell.
Nanoscale, 2022,14, 5214-5226
https://doi.org/10.1039/D1NR07918B
DNA self-assembled Au nanoparticle clusters on silver nanorod arrays for high-sensitive and multiplex detection of cancer-related biomarkers
A surface-enhanced Raman scattering sensor based on a functionalized multiple-armed tetrahedral DNA nanostructure immobilized silver nanorod array substrate and SERS tags is constructed to achieve both multiplex detection and enhanced sensitivity.
Nanoscale, 2022,14, 4538-4547
https://doi.org/10.1039/D2NR00133K
About this collection
This online collection from Nanoscale and Nanoscale Horizons showcases some of the recent Surface Enhanced Raman Sepctroscopy (SERS) papers published in the journals.
We hope you enjoy reading these articles!