Issue 12, 2022
From the journal:

Chemical Communications

CuCoFe Layered double hydroxides as laccase mimicking nanozymes for colorimetric detection of pheochromocytoma biomarkers†

Feng-Wei Huang,a   Ke Ma,a   Xiu-Wen Ni,a   Sheng-Lin Qiao ORCID logo *a  and  Ke-Zheng Chen ORCID logo *a  

* Corresponding authors

a Lab of Functional and Biomedical Nanomaterials, College of Materials Science and Engineering, Qingdao University of Science and Technology (QUST), Qingdao, P. R. China
E-mail: qiaosl@qust.edu.cn, kchen@qust.edu.cn

Abstract

A laccase catalyzed colorimetric biosensing approach is promising for the detection of pheochromocytoma biomarkers, yet suffers from the poor stability of enzymes and high cost for production. Here we report for the first time an easy to produce, cheap, stable and reliable laccase-mimicking CuCoFe-LDHzyme, which can catalyze the oxidation of pheochromocytoma biomarkers to form a chromogenic product for smartphone-based colorimetric detection.

Graphical abstract: CuCoFe Layered double hydroxides as laccase mimicking nanozymes for colorimetric detection of pheochromocytoma biomarkers

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Article information

DOI
https://doi.org/10.1039/D1CC06612A
Article type
Communication
Submitted
24 Huk 2021
Accepted
11 Sun 2022
First published
11 Sun 2022

Chem. Commun., 2022,58, 1982-1985

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CuCoFe Layered double hydroxides as laccase mimicking nanozymes for colorimetric detection of pheochromocytoma biomarkers

F. Huang, K. Ma, X. Ni, S. Qiao and K. Chen, Chem. Commun., 2022, 58, 1982 DOI: 10.1039/D1CC06612A

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