Issue 18, 2015

Porphyrin-functionalized mesoporous organosilica nanoparticles for two-photon imaging of cancer cells and drug delivery

Abstract

The synthesis of a zinc porphyrin derivative possessing eight triethoxysilyl groups was performed through a CuAAC-click reaction. This porphyrin was covalently entrapped in ethenylene-bridged mesoporous organosilica nanoparticles which efficiently allowed performing doxorubicin delivery and two-photon imaging of breast cancer cells.

Graphical abstract: Porphyrin-functionalized mesoporous organosilica nanoparticles for two-photon imaging of cancer cells and drug delivery

Supplementary files

Article information

Article type
Communication
Submitted
13 ก.พ. 2558
Accepted
10 เม.ย. 2558
First published
10 เม.ย. 2558

J. Mater. Chem. B, 2015,3, 3681-3684

Author version available

Porphyrin-functionalized mesoporous organosilica nanoparticles for two-photon imaging of cancer cells and drug delivery

C. Mauriello-Jimenez, J. Croissant, M. Maynadier, X. Cattoën, M. Wong Chi Man, J. Vergnaud, V. Chaleix, V. Sol, M. Garcia, M. Gary-Bobo, L. Raehm and J. Durand, J. Mater. Chem. B, 2015, 3, 3681 DOI: 10.1039/C5TB00315F

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