Nickel/AlMe2Cl-catalysed carbocyanation of alkynes using arylacetonitriles

Akira Yada; Tomoya Yukawa; Yoshiaki Nakao; Tamejiro Hiyama

doi:10.1039/B907290J

You do not have JavaScript enabled. Please enable JavaScript to access the full features of the site or access our non-JavaScript page.

Nickel/AlMe₂Cl-catalysed carbocyanation of alkynes using arylacetonitriles†‡

Akira Yada,^a Tomoya Yukawa,^a Yoshiaki Nakao*^a and Tamejiro Hiyama*^a

Author affiliations

* Corresponding authors

^a Department of Material Chemistry, Graduate School of Engineering, Kyoto University, Kyoto 615-8510, Japan
E-mail: yoshiakinakao@npc05.mbox.media.kyoto-u.ac.jp, thiyama@z06.mbox.media.kyoto-u.ac.jp
Fax: +81 75 383 2445
Tel: +81 75 383 2446

Abstract

Nickel/Lewis acid dual catalysis was found to effect the carbocyanation reaction of alkynes using arylacetonitriles, giving a range of triply substituted acrylonitriles; the reaction of optically active α-phenylpropionitrile suggested a reaction mechanism that involves oxidative addition of a C–CN bond with retention of its absolute configuration.

This article is part of the themed collection: Selective Catalysis for Organic Synthesis

Download options Please wait...

Supplementary files

Article information

DOI: https://doi.org/10.1039/B907290J
Article type: Communication
Submitted: 14 เม.ย. 2552
Accepted: 05 พ.ค. 2552
First published: 26 พ.ค. 2552

Download Citation

Chem. Commun., 2009, 3931-3933

Permissions

Request permissions

Nickel/AlMe₂Cl-catalysed carbocyanation of alkynes using arylacetonitriles

A. Yada, T. Yukawa, Y. Nakao and T. Hiyama, Chem. Commun., 2009, 3931 DOI: 10.1039/B907290J

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Social activity

Fetching data from CrossRef.
This may take some time to load.

Chemical Communications