Issue 26, 2009

Sc(OTf)3-catalyzed condensation of 2-alkyl-N-tosylaziridine with aldehydes or ketones: an efficient synthesis of 5-alkyl-1,3-oxazolidines

Abstract

Sc(OTf)3 effectively catalyzes the condensation of 2-alkyl-N-tosylaziridine with a wide variety of aldehydes and ketones, producing 5-alkyl-1,3-oxazolidines in good yields and excellent regioselectivity at catalyst loadings as low as 1 mol%.

Graphical abstract: Sc(OTf)3-catalyzed condensation of 2-alkyl-N-tosylaziridine with aldehydes or ketones: an efficient synthesis of 5-alkyl-1,3-oxazolidines

Supplementary files

Additions and corrections

Article information

Article type
Communication
Submitted
09 Feb 2009
Accepted
23 Mar 2009
First published
26 May 2009

Chem. Commun., 2009, 3928-3930

Sc(OTf)3-catalyzed condensation of 2-alkyl-N-tosylaziridine with aldehydes or ketones: an efficient synthesis of 5-alkyl-1,3-oxazolidines

B. Kang, A. W. Miller, S. Goyal and S. T. Nguyen, Chem. Commun., 2009, 3928 DOI: 10.1039/B902647A

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