Themed collection Journal of Materials Chemistry B Lunar New Year collection 2022

This review article highlights recent research progress on the NIR-responsive nanocomposite hydrogels, focusing on their preparation, properties, applications and future prospectus.

This paper reviews the recent progress in nitric oxide (NO) donors, biomaterial vectors, biomaterial-based NO delivery systems and NO synthetic enzyme mimics, and emphasizes the application potentials of NO releasing biomaterials in chronic wound healing.

In the presented perspective, the synthetic method, characterization, and research progress in tumor therapy based on CMMs have been summarized. Also the prospects and challenges of utilizing CMMs for tumor therapy have been discussed.

This review describes the recent progress in tissue adhesive hydrogel bioelectronics.

Using a proton-sensing transistor, changes in membrane permeability induced by transfection reagents were assessed, shedding light on endosomal escape mechanisms.

A PEGylated antibody with short PEG linkers was excreted faster to visualize tumors clearly with exceptionally high tumor-to-background ratio in nuclear imaging.

Gold nanoparticles (AuNPs) were surface-engineered with a cationic corona to enhance the incorporation of photosensitizers for PDT.

Virus detection is materialized by engineered polymeric nanoparticles as host cell-mimetic decoys and analysis of the kinetic stability of nanoparticles against fusion peptides provides insight into the design of influenza viruses detection system.

A smart supramolecular quaternary ammonium nanoparticle, namely quaternary ammonium PAMAM-AZO@CP[5]A (Q-P-A@CP[5]A) was designed to treat drug-resistant colorectal cancer (CRC) caused by Fusobacterium nucleatum.

An injectable self-healing HA–pAA hydrogel with LbL-PPMMs encapsulated can induce chondrocytes to form a deep columnar array for repairing the cartilage.

A facile strategy for the construction of an efficient chromophore reaction-based probe for biogenic amines detection was developed.

Plasmonic polystyrene nanopillars are fabricated by using anodized aluminum oxide (AAO) membranes as templates, and successfully employed for detection of specific antibodies in the pM range.

A fully water-soluble, bright, and red fluorescent BODIPY fluorophore can achieve high-resolution mitochondrial imaging with high biocompatibility, photostability and chemical stability.

An ECM-inspired heterogeneous bilayer hydrogel possesses similar components to natural tissue, promotes cell activity and exhibits good regeneration of osteochondral defects.

Interconnected collagen porous scaffolds were prepared using PLGA sponges as sacrificial templates and applied for cartilage tissue engineering.

A metallic solid-state adhesive for biological soft tissues was fabricated using Ti–6Al–4V alloys, and the influence of the minor β phase and the small amount of Al in the α phase are reported.

Facile-regulation of the multi-enzyme-mimicking activities and effective guidelines from radar analysis established here advance the further biomedical applications of ceria-based nanozymes.

Efficient photodynamic therapy using self-assembled nanogel comprising chlorin e6-bearing polysaccharide.

Antibody-functionalized, multiscale pore contained carbon nanofiber-based FET-type sensor exhibits ultrahigh sensitive and selectivity toward the epilepsy biomarker (NES1).

Label-free hepatitis B surface antigen electrochemical immunosensors by Cu-NH₂BDC MOFs.

A cellular multi-targeting strategy inspired by skin protein-derived peptides is proposed to direct skin therapies toward cellular targets.

The alleviation properties of a Pt-dendrimer nanozyme for GBM metastasis were introduced for the first time. The biological properties of the Pt-dendrimer nanozyme were demonstrated as a suppressor of GBM migration, invasion, and adhesion.

A GOX-hemin nanogel was prepared via polymerization on the surface of GOX, and it could be used as a one-step glucose detection system.

A nanodrug as a macromolecular therapeutic agent was developed for addressing drug resistance in cancer therapy. The multivalent interactions between the nanodrugs and cytosolic components reflected their cytotoxicity.

N-Cadherin mimetic nanofibrous biocompatible peptide hydrogels with enhanced mechanical properties for differentiation of mesenchymal stem cells into chondrocytes.

The superparamagnetic iron oxide nanoparticles have broad application prospects in the diagnosis and treatment of cancer.

Nanoparticles based double-acceptor conjugated polymers were developed by conventional methods. And subsequently NPs with bright NIR-II fluorescence signals and superior NIR-II PTT efficiency were successfully applied for NIR-II FI guided NIR-II PTT.

The marriage between 1550 nm (NIR-IIb) light excitation and dual-photodynamic therapy for upconversion UCNP@SiO₂/RB,Ce6-PEG nanoparticles to generate ¹O₂ showing a synergetic effect against pancreatic tumors in vitro and in vivo.

A dissolving microneedle patch for responsive insulin release and type 1 diabetes therapy.

An ER-targeting, intracellular delivery approach that utilizes cell-penetrating peptide-conjugated lipid/polymer hybrid nanovehicles is proposed.