Themed collection Celebrating Latin American Chemistry

Metal ions are implicated in many proteinopathies. Three case studies are discussed to address how copper binding impacts protein folding and aggregation, and its relevance in understanding the polymorphic nature of the aggregates related to disease.

Critical review of the advanced experimental approaches to measure the main thermodynamic parameters and to guide establishing the necessary conditions to perform a protein crystallization assay: methodologies, set-ups, and future directions.

A summary of the applications of MFM-300(Sc), as well as some emerging advanced applications, have been discussed.

In this perspective, different expert opinions are gathered on the definition and concept of aromaticity.

Natural products (NPs) are primarily recognized as privileged structures to interact with protein drug targets.

Central role of future professionals in chemistry to promote alternatives towards sustainability.

Photoluminescent chemosensors based on Zn and Cd coordination arrays for the sensitive and selective detection of pesticides, herbicides, and cyanide in aqueous environments.

This short review presents the latest advances in the field of electrochemical biosensors, focusing particularly on impedimetric biosensors for the direct measurement of analytes.

The present minireview summarizes recent advances in the application of metal halide perovskite for CO₂ photoreduction.

There is a considerable diversity of Brazilian berries, purple in color, and potentially rich in anthocyanins, which are an unexplored source of new foods, products, extracts, and compounds of economic and social interest.

This review article communicates the integration of metabolomics and genomics approaches to unravel the citrus host–pathogen interaction.

Fermentates are complex mixtures containing inactivated or viable lactic acid bacteria, growth metabolites and compatible culture medium for food applications, representing a practical and cost-effective alternative to cell-free supernatants.

Nanotechnology is a relatively new technological field, therefore, the information about the associated risk of nanomaterials in environmental and human health must be addressed and consolidated to develop accurate legislations, frameworks, and guidelines to standardise a safe use in any field.

Green synthesized bimetallic nanoparticles may be recognized as key nanotechnological tools to provide disruptive and effective strategies to reach the Sustainable Developments Goals (SDGs).

This review provides a comprehensive summary of the utilization of ammonia replacements in synthesizing protected and free primary amines, encompassing both traditional reagents and the latest developments.

This review summarizes plant metabolites targeting crucial enzymes involved in glucose homeostasis useful for antidiabetic drug development.

Pheromones are generally produced by insects in submicrogram amounts which makes it difficult to elucidate their chemical structures. Synthetic approaches are therefore necessary for the unambiguous identification of these natural products.

Selenonium and telluronium salts are useful reagents in organic transformations. Their application and comparisons with sulfonium analogues are presented herein.

Transition metal catalysed C–S bond formation from unreactive C–H bonds is a remarkable tool in the late-stage functionalization of complex molecules. This review highlights significant advances and mechanistic analyses from the last two decades.

Microbial trans-sialidases regioselectevely incorporate sialic acids into oligosaccharides without the need of an activated nucleotide.

The methods for the synthesis of deoxy sugars, involving deoxygenation and glycosidation, give access to useful molecules for multiple purposes.

In this review we focus on the recent progress and current trends in biomass carbon-based composites containing mono-, bi- and trimetallic metal oxides and hydroxides for supercapacitor applications.

A broad variety of α-aminoamide-based compounds have been synthesized via the three-component version of the Ugi reaction (U-3CR) or by any of its variants (Ugi-Zhu-3CR, Orru-3CR, Ugi-4C-3CR, Ugi-Joullié-3CR, GBB-3CR, Ugi-Reissert-3CR, and so on).

This review critically addresses the most relevant and innovative techniques for obtaining polymers from tannins.

In this review, we focus in all aspects of NMR simulation of natural products, from the fundamentals to the new computational toolboxes available, combining advanced quantum chemical calculations with upstream data processing and machine learning.

Coupling hydrothermal liquefaction with anaerobic digestion can recover between 54 and 99% of the energy contained in organic wastes, while reducing up to 92% of the chemical oxygen demand of the influent stream.

This feature review is focused on recent approaches for removing versatile directing groups.

Plant alkaloids are natural secondary metabolites that have attracted great interest in the development of drugs for therapeutic applications due to their diverse bioactivities.

The water–energy–food nexus aims to achieve sustainable development by meeting present needs while safeguarding the capacity of future generations.

This study proposes a mitochondrial targeting optimization by uncovering the synergistic influence of Nernst potential and partitioning contributions, reshaping our understanding of cellular localization.

Carbon microfibers (CMFs) are low-cost and robust SO₂ adsorbents, exhibiting cyclability, good SO₂/CO₂ selectivity, and photoluminescence response to SO₂.

An alkene-derived zwitterionic ligand was used to control the morphology of CsPbBr₃ perovskite nanocrystals, showcasing the first example of a surfactant-tail controlled growth.

A greener, simple and safe methodology for the chemoselective reduction of benzylidene thiazolidine-2,4-diones and heterocycles is described. To demonstrate the synthetic utility of this transformation, Pioglitazone API was prepared in 81% yield.

The nature of the metal center can be used to tune the charge transfer rate in MOFs.

Computational studies have shown that two positrons can stabilize three repelling atomic anions through the formation of a three-center positronic bond.

Self-assembled nanostructures derived from lipids and polymers are investigated as potential drug delivery vehicles in nanomedicine.

Isothiazolinones are a class of heterocyclic compounds extensively employed in a variety of applications, including as biocides in cosmetics, detergents, and paints, as well as in industrial wastewater treatment.

This study discloses the design of nanohybrid Biomass@MOF resulting from the functionalization of a hydrochar (HC) through hydrothermal treatment (HT) of corn cob residues and MIL-53(Al).

We proposed an accurate pXRF matrix-matched calibration method for the elemental analysis of ground-roasted coffee as well as the corresponding spent coffee grounds (SCG).

We identified the significant technical-economic factors, uncertainty, and risks in the pine sawdust biorefinery design for bioethylene and lignin production.

A tissue engineering device for bone repair was prepared using a polymeric collagen-decorated scaffold. Functionalization with cysteine and further bioconjugation with collagen improved hydrophilicity, cell viability, and mineralization.

The polymerization procedure reduces the aminolysis drawback found in conventional synthesis for renewable polyhydroxyurethanes. The polymer is from two macaw palm oil derivatives and presents flexible, luminescent, and waterproofing features.

Light-activated molecular motors rotate at a similar frequency in polymersomes and in solution.

Office paper has been explored as a simple, inexpensive, and global platform for manufacturing microfluidic paper-based analytical devices through a laser printer.

This study aimed to explore the antibacterial and anticancer potential of biosynthesized silver nanoparticles and how the biosynthesis of AgNP@Bio determines their biological roles.

Three palladium(II) complexes bearing galactopyranoside-based NHC ligands have been synthesized. Catalytic studies reveal that the complexes are active and reusable.

The use of the spent coffee grounds–alginate biocomposite, a low-cost adsorbent, removes methylene blue, an organic dye that persists in the environment and is harmful to the ecosystems.

Pure porous silica zeolite adsorbents with framework surface faults, in the form of siloxy groups, are selective toward single- or multi-component linear siloxanes for removal from water.

This study presents the development of a polyester microplate for detecting the S-protein of the SARS-CoV-2 virus in saliva and nasopharyngeal swab samples using direct enzyme-linked immunosorbent assay (ELISA) technology.

Dopamine (DA) and uric acid (UA), vital components, cause several health problems if their concentrations are altered; so, the determination of DA and UA is turned to be essential in real samples.

Urban stormwater sediments are associated with non-point source pollution that poses risks to the environment and human health.

Nanopaper made of bacterial nanocellulose and sensitizing agents such as CdTe quantum dots and dithizone acting as a chemosensor in heavy metal detection; insight into the nanopaper assembly, structural, morphological, and superficial characterization, and heavy metal evaluation in aqueous solution.

Inverse design of fluorescent biomarkers by means of electronic, conjugation and push-pull effects.

Peptide structure–activity/property relationship (P-SA/PR) studies focus on understanding how the structural variations of peptides influence their biological activities and other functional properties.

This study combines operando XRD & Raman spectroscopy and DFT simulation to reveal how Li₂CO₃ formation and reversibility may contribute to energy storage in supercapacitors.

Supported and free-standing MoS₂ monolayers were patterned using a focused ion beam to tune their electrocatalytic activity toward H₂ production. Defects can either be confined near the etched interfaces or spread depending on the applied dose.

Exploring the art of tailoring electronic and phonon properties in a few layers of Bi₂Te₃ crystals through layer variation with Raman spectroscopy.

A wide color gamut of electrochromic polymers (ECPs), presenting controllable color switching, is described here based on a selective combination of transparent films of polythiophene, polyaniline and poly(3,4-ethylenedioxythiophene) (PEDOT).

Biochar electrodes can attain current densities similar to graphite while being more cost-effective and environmentally friendly.

The addition mechanism of the OH-initiated oxidation of allyl methyl sulfide (AMS) under atmospheric conditions was studied theoretically using both density functional theory (DFT) and the SVECV-f12 composite method.

DA adducts obtained from chitin-derived furans underwent dehydration reactions ultimately leading to the synthesis of N-containing aromatics, including phthalimides.

This study reports the development of zein nanoparticles associated with the herbicide atrazine and the pre-emergence activity of this formulation against a target and a non-target plant, its soil mobility and uptake/transport in plant tissues.

Cellulose-based hydrogels with antifouling properties reduce the formation of bacterial biofilms.

A novel efficient one-step synthetic strategy for the preparation of the antiviral favipiravir from with the available 3-hydroxy-2-pyrazinecarboxamide and Selectfluor® was developed, the use of an IL being essential.

The optical studies of three macrocyclic Er^III complexes showed visible upconversion and NIR-downshifted emission upon metal centred excitation. Besides, macrocyclic ligands with aliphatic spacers act as antennas to sensitize the Er^III luminescence.

We have investigated the possibility of using aluminum functionalized silicene trilayers (ABC-Si₄Al₂) as an anode material for alkali metal ion batteries (AMIBs).

A high-CT organic fluorophore featuring an internal weak basic moiety to promote a selectively diverse PCET mechanism upon excitation.

Lateral dimension of graphene oxide increases the modulus and bactericide properties of methacrylated gelatin nanocomposite hydrogels.

This paper describes the recognition process of tetrahedral [Cu^II(tnz)₂X₂] (X = Cl, Br) complexes by a DNA chain, analyzing the specific interaction between the DNA bases and backbone with the metal and the tinidazole (tnz) ligand.