Issue 46, 2005
From the journal:

Chemical Communications

Multivalent, bifunctional dendrimers prepared by click chemistry†

Peng Wu,a   Michael Malkoch,b   Jasmine N. Hunt,b   Robert Vestberg,b   Eiton Kaltgrad,a   M. G. Finn,*a   Valery V. Fokin,*a   K. Barry Sharpless*a  and  Craig J. Hawker*b  

* Corresponding authors

a The Scripps Research Institute, Department of Chemistry, BCC-315 10550 N. Torrey Pines Rd., La Jolla, USA
E-mail: sharples@scripps.edu
Fax: +1 858 784 7562
Tel: +1 858 784 7515

b Materials Research Laboratories, University of California, Santa Barbara, USA
E-mail: hawker@mrl.ucsb.edu
Tel: +1 805 893 7161

Abstract

Unsymmetrical dendrimers, containing both mannose binding units and coumarin fluorescent units, have been prepared using click chemistry and shown to be highly efficient, dual-purpose recognition/detection agents for the inhibition of hemagglutination.

Graphical abstract: Multivalent, bifunctional dendrimers prepared by click chemistry

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Article information

DOI
https://doi.org/10.1039/B512021G
Article type
Communication
Submitted
24 aug 2005
Accepted
21 okt 2005
First published
04 nov 2005

Chem. Commun., 2005, 5775-5777

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Multivalent, bifunctional dendrimers prepared by click chemistry

P. Wu, M. Malkoch, J. N. Hunt, R. Vestberg, E. Kaltgrad, M. G. Finn, V. V. Fokin, K. B. Sharpless and C. J. Hawker, Chem. Commun., 2005, 5775 DOI: 10.1039/B512021G

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