Issue 24, 2003

Polymer-assisted solution phase synthesis of the antihyperglycemic agent Rosiglitazone (Avandia™)

Abstract

The commercially important antihyperglycemic agent Rosiglitazone 1 (Avandia™) has been prepared in high purity by a multi-step, polymer-assisted solution phase (PASP) synthesis without the need for the conventional chromatographic purification of any intermediates.

Graphical abstract: Polymer-assisted solution phase synthesis of the antihyperglycemic agent Rosiglitazone (Avandia™)

Supplementary files

Article information

Article type
Paper
Submitted
03 júl 2003
Accepted
22 okt 2003
First published
06 nov 2003

Org. Biomol. Chem., 2003,1, 4392-4395

Polymer-assisted solution phase synthesis of the antihyperglycemic agent Rosiglitazone (Avandia™)

X. Li, C. Abell, B. H. Warrington and M. Ladlow, Org. Biomol. Chem., 2003, 1, 4392 DOI: 10.1039/B307549D

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements