Issue 23, 2018

Visible-light-mediated allylation of alkyl radicals with allylic sulfones via a deaminative strategy

Abstract

A visible-light-mediated radical allylation of primary amine-derived Katritzky salts with allylic sulfones via C(sp3)–N bond activation is reported, furnishing the corresponding alkenes in satisfactory yields. This mild protocol provides an efficient strategy for site-specific C(sp3)–C(sp3) bond formation using abundant feedstock primary amines, particularly α-amino acids as alkyl radical precursors. This photocatalytic reaction demonstrates a broad substrate scope and good functional group tolerance.

Graphical abstract: Visible-light-mediated allylation of alkyl radicals with allylic sulfones via a deaminative strategy

Supplementary files

Article information

Article type
Research Article
Submitted
28 set 2018
Accepted
18 out 2018
First published
19 out 2018

Org. Chem. Front., 2018,5, 3443-3446

Visible-light-mediated allylation of alkyl radicals with allylic sulfones via a deaminative strategy

M. Zhang and F. Liu, Org. Chem. Front., 2018, 5, 3443 DOI: 10.1039/C8QO01046C

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements