Issue 89, 2021

Nanomicelle-enhanced, asymmetric ERED-catalyzed reductions of activated olefins. Applications to 1-pot chemo- and bio-catalysis sequences in water

Abstract

Bio-catalytic reactions involving ene-reductases (EREDs) in tandem with chemo-catalysis in water can be greatly enhanced by the presence of nanomicelles derived from the surfactant TPGS-750-M. Transformations are provided that illustrate the variety of sequences now possible in 1-pot as representative examples of this environmentally attractive approach to organic synthesis.

Graphical abstract: Nanomicelle-enhanced, asymmetric ERED-catalyzed reductions of activated olefins. Applications to 1-pot chemo- and bio-catalysis sequences in water

Supplementary files

Article information

Article type
Communication
Submitted
31 aug 2021
Accepted
04 okt 2021
First published
04 okt 2021

Chem. Commun., 2021,57, 11847-11850

Nanomicelle-enhanced, asymmetric ERED-catalyzed reductions of activated olefins. Applications to 1-pot chemo- and bio-catalysis sequences in water

N. Akporji, V. Singhania, J. Dussart-Gautheret, F. Gallou and B. H. Lipshutz, Chem. Commun., 2021, 57, 11847 DOI: 10.1039/D1CC04774D

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