Issue 81, 2018

Cyanomethyl anion transfer reagents for diastereoselective Corey–Chaykovsky cyclopropanation reactions

Abstract

A readily available and bench-stable cyanomethyl sulfonium salt was used in highly diastereoselective Corey–Chaykovsky cyclopropanation reactions of electron-poor olefins. This efficient method provides a rapid route to access densely functionalized cyclopropyl nitriles.

Graphical abstract: Cyanomethyl anion transfer reagents for diastereoselective Corey–Chaykovsky cyclopropanation reactions

Supplementary files

Article information

Article type
Communication
Submitted
11 jul 2018
Accepted
20 sep 2018
First published
20 sep 2018

Chem. Commun., 2018,54, 11439-11442

Cyanomethyl anion transfer reagents for diastereoselective Corey–Chaykovsky cyclopropanation reactions

R. Hommelsheim, K. J. Hock, C. Schumacher, M. A. Hussein, T. V. Nguyen and R. M. Koenigs, Chem. Commun., 2018, 54, 11439 DOI: 10.1039/C8CC05602A

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements