Issue 11, 2022

Enhanced mechanical performance and wettability of PHBV fiber blends with evening primrose oil for skin patches improving hydration and comfort

Abstract

The growing problem of skin diseases due to allergies often causing atopic dermatitis, which is characterized by itching, burning, and redness, constantly motivates researchers to look for solutions to soothe these effects by moisturizing skin properly. For this purpose, we combined poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) electrospun fibers with evening primrose oil (EPO) into a system of patches to ensure skin hydration. Moreover, the dressing or patch application requires appropriate stretchability and wettability of the electrospun material. Thus, we examined the mechanical properties of the PHBV blend with EPO, as well as changes in wettability of the fiber surface depending on the share of EPO additive in the blend. The effectiveness of the patches has been characterized using the water vapor transmission rate as well as by the skin moisturizing index. The thermal insulation effect of the patches on human skin has been verified as well. The patches made by combining the polymer with natural oil showed enhanced mechanical properties and increased skin hydration, indicating the potential applicability of PHBV-based patches. The presented discovery of PHBV patches with EPO is a prospective and alternative treatment for patients for whom current state-of-the-art methods do not bring satisfactory results.

Graphical abstract: Enhanced mechanical performance and wettability of PHBV fiber blends with evening primrose oil for skin patches improving hydration and comfort

Supplementary files

Article information

Article type
Paper
Submitted
21 dec 2021
Accepted
08 feb 2022
First published
07 mrt 2022
This article is Open Access
Creative Commons BY license

J. Mater. Chem. B, 2022,10, 1763-1774

Enhanced mechanical performance and wettability of PHBV fiber blends with evening primrose oil for skin patches improving hydration and comfort

Ł. Kaniuk, A. Podborska and U. Stachewicz, J. Mater. Chem. B, 2022, 10, 1763 DOI: 10.1039/D1TB02805G

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. You can use material from this article in other publications without requesting further permissions from the RSC, provided that the correct acknowledgement is given.

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