Themed collection 2026 RSC Advances Popular Advances Collection

ICG-loaded nanoparticles are not merely delivery tools, but rather integrated theranostic systems that combine targeted drug release, precision photodynamic therapy, and immune activation—laying the groundwork for more effective and safer next-generation cancer therapies.

Pyrazolo[1,5-a]pyrimidine is a privileged heterocycle, which makes it a potent target in drug discovery and medicinal and coordination chemistry. Pyrazolopyrimidines have unique structural features, great chemical stability and enormous biological applicability.

A microfluidic platform that enables co-culture and focal irradiation under closed microenvironments, providing a robust approach for analyzing intercellular communication.

A base-promoted, transition-metal-free one-pot method for the divergent synthesis of tricyclic furo[3,2-e]indolizines is described.

The increasing prevalence of levofloxacin (LV) and related antibiotics in aquatic systems constitutes a critical environmental and public health concern, driving the need for advanced water treatment solutions.

A biphasic dissolving microneedle platform integrating HP-β-cyclodextrin inclusion complexes enables high drug loading and efficient transdermal delivery of poorly soluble drugs, supporting improved bioavailability and translational potential.

In this work, we explore the possibility of applying automated crystal structure prediction to reproduce the experimentally identified metastable porous polymorphs.

A morphology-controlled spherical 58S bioactive glass was used to load Andrographis paniculata extract , creating a multifunctional composite suitable for dental applications.

Systematic investigations of the structure–defect–property relationships revealed a tripartite mechanism through which temperature annealing regulates film behavior.

Cholesterol-modified Clematis filamentosa Dunn nanovesicles (CHOL@CDNVs) reprogram macrophages toward M2 polarization, alleviating inflammation, edema, and early fibrosis in acute lung injury.

Fatty acids derived from waste cooking oil (WCO) are successfully processed as sustainable phase-change materials (PCMs) for thermal energy storage.

A series of novel (p-tolylthio)methyl-linked 1,2,3-triazole derivatives 10–17 was synthesized via Cu(I)-catalyzed click chemistry and structurally characterized.

We proposed a high-copper-content metal–organic framework through multiple Cu–O coordination for potential antibacterial applications.

An innovative and efficient synthetic route featuring DDQ-promoted cascade oxidation, cyanation/cyclization to produce 2-benzoylbenzofurans and benzofuro[2,3-c]pyridines from 2′-hydroxyethyl cinnamate and phenacyl bromides has been developed.

A solar-powered bioelectrochemical system integrates a photovoltaic bias with a bioanode to enable cadmium remediation and recovery under mild aqueous conditions, favoring precipitation of Cd–O solids over metallic deposition.

The amendment of electronic structures in heterogeneous catalysts has mainly been established as one of the most efficient approaches for enhancing catalytic performances in redox reactions.