Themed collection 2024 Chemical Science HOT Article Collection
Opportunities and challenges for plastic depolymerization by biomimetic catalysis
This perspective highlights the challenges and opportunities in achieving sustainable plastic recycling under mild conditions by imitating the active sites and the substrate-binding clefts of enzymes.
Chem. Sci., 2024,15, 6200-6217
https://doi.org/10.1039/D4SC00070F
Revisiting poly(vinyl chloride) reactivity in the context of chemical recycling
An overview of PVC functionalization through the lens of chemical recycling.
Chem. Sci., 2024,15, 5802-5813
https://doi.org/10.1039/D3SC06758K
Connecting chemical worlds for a sustainable future
While chemistry has a role as the central science, other sciences are also central to solving the problems that lie ahead. To be more effective in this endeavor, we need to connect disciplines and break down the silos that artificially separate them.
Chem. Sci., 2024,15, 5056-5060
https://doi.org/10.1039/D3SC06815C
Hybrid and composite materials of organic crystals
Combining organic crystals and polymers results in a new class of all-organic, lightweight, flexible materials with unprecedented mechanical robustness, resilience, and diversity in combination with other functional materials.
Chem. Sci., 2024,15, 2684-2696
https://doi.org/10.1039/D3SC06469G
Adamantane-type clusters: compounds with a ubiquitous architecture but a wide variety of compositions and unexpected materials properties
Adamantane-type clusters exhibit a huge diversity of chemical compositions, structural details, and resulting properties.
Chem. Sci., 2024, Advance Article
https://doi.org/10.1039/D4SC01136H
Hard carbon for sodium-ion batteries: progress, strategies and future perspective
Recent progress of preparation approaches for HCs is systematically overviewed, with a special focus on the comparison between traditional fabrication methods and advanced strategies regarding their influence on performance.
Chem. Sci., 2024,15, 6244-6268
https://doi.org/10.1039/D4SC00734D
The status and challenging perspectives of 3D-printed micro-batteries
Recent advances and present status of 3D-printed micro-batteries with respect to the connection between printable materials and printing techniques, as well as the rational design considerations are summarized.
Chem. Sci., 2024,15, 5451-5481
https://doi.org/10.1039/D3SC06999K
Recent advances in electrolyte molecular design for alkali metal batteries
In response to societal developments and the growing demand for high-energy-density battery systems, alkali metal batteries (AMBs) have emerged as promising candidates for next-generation energy storage.
Chem. Sci., 2024,15, 4238-4274
https://doi.org/10.1039/D3SC06650A
Synthesis of polyoxothiometalates through site-selective post-editing sulfurization of polyoxometalates
Chem. Sci., 2024, Accepted Manuscript
https://doi.org/10.1039/D4SC02912G
Key structural features to favour imines over hydrates in water: pyridoxal phosphate as a muse
The key structural features that aldehydes should present to favour imines over hydrates in water are investigated at different pD values. Sulfonate ortho-substituents remarkably stabilize iminium derivatives while disfavouring hydrate formation.
Chem. Sci., 2024, Advance Article
https://doi.org/10.1039/D4SC02206H
Structural-model-based genome mining can efficiently discover novel non-canonical terpene synthases hidden in genomes of diverse species
Non-canonical terpene synthases with primary sequences that are unrecognizable as canonical terpene synthases could be discovered through structural-model-based genome mining.
Chem. Sci., 2024, Advance Article
https://doi.org/10.1039/D4SC01381F
Site-selective S-gem-difluoroallylation of unprotected peptides with 3,3-difluoroallyl sulfonium salts
Bench-stable 3,3-difluoroallyl sulfonium salts proved to be versatile fluoroalkylating reagents for site-selective S-gem-difluoroallylation of cysteine residues in unprotected peptides. The newly added functional groups are poised for ligation.
Chem. Sci., 2024, Advance Article
https://doi.org/10.1039/D4SC02681K
Neutral inverse-sandwich rare-earth metal complexes of the benzene tetraanion
Neutral inverse-sandwich rare-earth metal complexes of the parent benzene tetraanion with an [M3+–(C6H6)4−–M3+] core electronic structure were synthesized and characterized. They behave as a four-electron reductant to reduce unsaturated substrates.
Chem. Sci., 2024,15, 8740-8749
https://doi.org/10.1039/D4SC02491E
β-Terrecyclene synthase constructs the quadrane backbone in terrecyclic acid biosynthesis
The construction of a quadrane scaffold by β-terrecyclene synthase via Coates' route is demonstrated through mutagenesis and isotopically sensitive branching studies. Subsequent enzymatic modifications convert β-terrecyclene into terrecyclic acid.
Chem. Sci., 2024,15, 8750-8755
https://doi.org/10.1039/D4SC01208A
4f-Orbital Mixing Increases the Magnetic Susceptibility of Cp′3Eu
Chem. Sci., 2024, Accepted Manuscript
https://doi.org/10.1039/D4SC01300J
Pathway-dependent supramolecular polymerization by planarity breaking
Chem. Sci., 2024, Accepted Manuscript
https://doi.org/10.1039/D4SC02499K
A Pd-catalyzed route to carborane-fused boron heterocycles
A Pd-catalyzed cross-coupling system has been developed to achieve vicinal diamination of 9,10-dibromo-carborane with NH-heterocycles and anilines. These products can be further converted to carborane-fused six- and seven-membered heterocycles.
Chem. Sci., 2024, Advance Article
https://doi.org/10.1039/D4SC02214A
Tricyclononenes and tricyclononadienes as efficient monomers for controlled ROMP: understanding structure–propagation rate relationships and enabling facile post-polymerization modification
A tricyclononene and tricyclononadiene monomer library is studied experimentally and computationally to deepen understanding of structure propagation rate relationships in ROMP. A novel poly(tricyclononadiene) post-ROMP functionalization is explored.
Chem. Sci., 2024,15, 8334-8345
https://doi.org/10.1039/D4SC01986E
Visualizing partial solvation at the air–water interface
To understand the solvation environment at the air–water interface, we use an azide vibrational reporter. The probe is sensitive to hydrogen bonding and electrostatics of the interface.
Chem. Sci., 2024,15, 8346-8354
https://doi.org/10.1039/D4SC01311E
High-efficiency color-tunable ultralong room-temperature phosphorescence from organic–inorganic metal halides via synergistic inter/intramolecular interactions
A high-efficiency, color-tunable ultralong RTP system based on metal-halide hybrids has been developed, which shows forward-looking application prospects in the fields of information encryption, anti-counterfeiting and dynamic optical data storage.
Chem. Sci., 2024, Advance Article
https://doi.org/10.1039/D4SC01630K
Real-time investigation of reactive oxygen species and radicals evolved from operating Fe–N–C electrocatalysts during the ORR: potential dependence, impact on degradation, and structural comparisons
Hydroxyl radical and hydrogen peroxide are implicated in the poor stability of Fe–N–C catalysts. We use SECM to detect these transient species in real time to evaluate their possible sources and relationship to stability.
Chem. Sci., 2024, Advance Article
https://doi.org/10.1039/D4SC01553C
A strategy for the controllable generation of organic superbases from benchtop-stable salts
Benchtop-stable organic superbase (SB) carboxylate salts, when paired with an epoxide in situ, controllably generate netural superbases for reaction applications.
Chem. Sci., 2024, Advance Article
https://doi.org/10.1039/D4SC02524E
Facile synthesis of a hydrazone-based zinc(II) complex for ferroptosis-augmented sonodynamic therapy
This work reports a facilely synthesized zinc(II) complex based on a hydrazone ligand for ferroptosis-augmented sonodynamic therapy.
Chem. Sci., 2024, Advance Article
https://doi.org/10.1039/D4SC02102A
Azole reagents enabled ligation of peptide acyl pyrazoles for chemical protein synthesis
A novel strategy is herein introduced which utilizes azole additives to activate the weak acyl donor peptidyl N-acyl pyrazole, and thereby enables its direct ligation to an N-terminal cysteine peptide for efficient chemical protein synthesis.
Chem. Sci., 2024,15, 7965-7974
https://doi.org/10.1039/D3SC06697E
Acridine photocatalysis enables tricomponent direct decarboxylative amine construction
Diverse amines and amino acids are now readily accessed from carboxylic acids, aldehydes, and amine precursors in a direct decarboxylative reaction enabled by a homogeneous triple catalytic system based on acridine photocatalysis.
Chem. Sci., 2024, Advance Article
https://doi.org/10.1039/D4SC02356K
Cross-linked K0.5MnO2 nanoflower composites for high rate and low overpotential Li–CO2 batteries
The synergistic effect between ultra-thin K0.5MnO2 nanoflowers and CNTs effectively promotes the nucleation and charging decomposition of Li2CO3, achieving low overpotential and high average energy efficiency as a Li–CO2 cathode.
Chem. Sci., 2024, Advance Article
https://doi.org/10.1039/D4SC01799D
Mechanistic investigations of the Fe(II) mediated synthesis of squaraines
In situ monitoring and reaction sampling (IR, NMR, EPR, Mössbauer spectroscopy) and structural characterisation of isolable species allows detailed mechanistic insight into the scission/homologation of CO by two-coordinate iron terphenyl complexes.
Chem. Sci., 2024, Advance Article
https://doi.org/10.1039/D4SC01286K
Copper-catalysed perarylation of cyclopentadiene: synthesis of hexaarylcyclopentadienes
The development of a copper-catalysed direct hexaarylation of cyclopentadiene under microwave activation allowed the synthesis of a family of unprecedented hexaarylcyclopentadienes.
Chem. Sci., 2024, Advance Article
https://doi.org/10.1039/D4SC02458C
Highly intense NIR emissive Cu4Pt2 bimetallic clusters featuring Pt(I)–Cu4–Pt(I) sandwich kernel
NIR phosphorescent Cu–Pt bimetallic clusters have been synthesized with solid-state quantum yield (QY) of up to 36.7%. Ligand effects enhances emission intensity and modulates emission wavelength via intra- and inter-molecular interactions.
Chem. Sci., 2024,15, 7552-7559
https://doi.org/10.1039/D4SC01022A
Continuous flow synthesis and post-synthetic conversion of single-crystalline covalent organic frameworks
Single-crystalline 2D covalent organic frameworks were synthesized in flow with laboratory scale rates of more than 1 g h−1.
Chem. Sci., 2024,15, 7545-7551
https://doi.org/10.1039/D4SC01128G
Nanoscale and chiral metal–organic frameworks for asymmetric reactions in water: bridging Lewis acid catalysis and biological systems
A new chiral UiO-type MOF with scandium tris(dodecyl sulfate) showed superior catalytic performance to the usual micellar catalysis in the presence of proteins, demonstrating the ability to prevent active Lewis acid sites from mortiferous deactivation.
Chem. Sci., 2024, Advance Article
https://doi.org/10.1039/D4SC01343C
Achieving pure room temperature phosphorescence (RTP) in phenoselenazine-based organic emitters through synergism among heavy atom effect, enhanced n → π* transitions and magnified electron coupling by the A–D–A molecular configuration
Synergism among heavy atom effect, enhanced n → π* transitions and magnified electron coupling to promote pure RTP emission.
Chem. Sci., 2024, Advance Article
https://doi.org/10.1039/D4SC01200C
Highly acidic N-triflylphosphoramides as chiral Brønsted acid catalysts: the effect of weak hydrogen bonds and multiple acceptors on complex structures and aggregation
An in-depth analysis including NMR-spectroscopy at 180 K and computer simulations suggests an OHN hydrogen bond between the phosphoramide oxygen and the imine instead of the mostly proposed NHN H-bond in binary NTPA/imine complexes.
Chem. Sci., 2024, Advance Article
https://doi.org/10.1039/D4SC01939C
A high-resolution structural characterization and physicochemical study of how a peptoid binds to an oncoprotein MDM2
How a peptoid binds to a protein was revealed by a co-crystal structure and systematic physicochemical studies.
Chem. Sci., 2024,15, 7051-7060
https://doi.org/10.1039/D4SC01540A
A dynamic cascade DNA nanocomplex to synergistically disrupt the pyroptosis checkpoint and relieve tumor hypoxia for efficient pyroptosis cancer therapy
A DNA nanocomplex with cascade DNAzymes, promoter-like ZnO2–Mn nanozymes and intercalated photosensitizers was designed to synergistically disrupt autophagy and relieve tumor hypoxia for efficient pyroptosis therapy.
Chem. Sci., 2024,15, 7079-7091
https://doi.org/10.1039/D4SC01147C
A tin analogue of propadiene with cumulated CSn double bonds
The first stable linear 2-stannapropadiene has been synthesized. The inert-pair effect favors Sn2+, but silyl substituents can counter it, enabling the isolation of 2-stannapropadiene with a Sn4+.
Chem. Sci., 2024,15, 7072-7078
https://doi.org/10.1039/D4SC00093E
Thermoswitchable catalysis to inhibit and promote plastic flow in vitrimers
We show that weaker acid catalysis has profound effects on the dynamicity of vinylogous urethane based polymer networks. Moreover, the dynamicity could be adjusted by changing electronic and steric parameters in the catalytic environment.
Chem. Sci., 2024,15, 7061-7071
https://doi.org/10.1039/D4SC00417E
100% selective cyclotrimerization of acetylene to benzene on Ag(111)
If a critical acetylene surface coverage threshold above one monolayer is attained, acetylene conversion to benzene occurs with 100% selectivity on Ag(111). The presence of multiple monolayers has the unforeseen effect of increasing benzene production while maintaining selectivity.
Chem. Sci., 2024,15, 6716-6725
https://doi.org/10.1039/D4SC01053A
Ultrafast photogeneration of a metal–organic nitrene from 1,1′-diazidoferrocene
A bent azide intermediate is key to form 1-azido-1′-nitrenoferrocene from 1,1′-diazidoferrocene, as shown with UV-pump–mid-IR-probe transient absorption spectroscopy and density functional theoryTD-DFT calculations including spin–orbit coupling.
Chem. Sci., 2024,15, 6707-6715
https://doi.org/10.1039/D4SC00883A
Unraveling the mechanisms of triplet state formation in a heavy-atom free photosensitizer
Triplet excited states play a pivotal role in photosensitizers. Detailed simulations reveal how these states are formed efficiently in heavy-atom free systems.
Chem. Sci., 2024,15, 6726-6737
https://doi.org/10.1039/D4SC01369G
High-throughput single-cell mass spectrometry enables metabolic network analysis by resolving phospholipid CC isomers
A high-throughput single-cell MS platform that can perform both lipid profiling and unsaturated lipid CC location isomer resolution analysis was developed, which can be effectively used for in-depth structural lipid metabolism network analysis.
Chem. Sci., 2024,15, 6314-6320
https://doi.org/10.1039/D3SC06573A
Seeing is believing: what is on the surface of silver nanocrystals suspended in their original reaction solution
Surface-enhanced Raman scattering was used to resolve the chemical species, including chloride ions, on the surface of Ag nanocrystals in their original reaction solution, avoiding changes to the surface while eliminating possible artifacts.
Chem. Sci., 2024,15, 6321-6330
https://doi.org/10.1039/D4SC00730A
Manipulating the functionality and structures of π-conjugated polymers utilizing intramolecular noncovalent interactions towards efficient organic photovoltaics
We synthesized a series of naphthobisthiadiazole-polymers by systematically introducing the alkyl, ester, and fluorine groups in the quaterthiophene co-unit and studied the effect of noncovalent interactions on physical and photovoltaic properties.
Chem. Sci., 2024,15, 6349-6362
https://doi.org/10.1039/D4SC00899E
Streamlining the automated discovery of porous organic cages
Efficiently merging low-cost high-throughput screening and characterisation, automated data analysis, computational modelling, and cagey – a custom database analysis tool, enhances large-scale data curation and accelerates discovery of organic cages.
Chem. Sci., 2024,15, 6331-6348
https://doi.org/10.1039/D3SC06133G
Electronic isomerism in a heterometallic nickel–iron–sulfur cluster models substrate binding and cyanide inhibition of carbon monoxide dehydrogenase
A protein-based model of carbon monoxide dehydrogenase displays distinct X-ray absorption, EPR, and vibrational signatures upon CO and CN− binding that support ligand-dependent electronic rearrangement throughout the nickel–iron–sulfur core.
Chem. Sci., 2024,15, 5916-5928
https://doi.org/10.1039/D4SC00023D
Efficient automated solid-phase synthesis of recognition-encoded melamine oligomers
An automated solid-phase synthesis route has been developed to rapidly synthesise recognition-encoded melamine oligomer sequences up to 42 monomer units long in remarkably high yield and excellent crude purity.
Chem. Sci., 2024,15, 5957-5963
https://doi.org/10.1039/D4SC00973H
Reactivity of α-diazo sulfonium salts: rhodium-catalysed ring expansion of indenes to naphthalenes
Cyclopropyl-substituted sulfonium salts are obtained by Rh-catalysed addition of α-diazo dibenzothiophenium salts to olefins. When indenes are used as substrates, initially formed cyclopropyl rings open with concomitant elimination of dibenzothiophene, enabling access to 2-substituted naphthalenes.
Chem. Sci., 2024,15, 5938-5943
https://doi.org/10.1039/D4SC01138D
Fluorescent carbazole-derived α-amino acids: structural mimics of tryptophan
Unnatural α-amino acids bearing carbazole side-chains have been shown to be effective structural mimics of tryptophan in peptides and valuable fluorescent probes for the analysis of protein–protein interactions.
Chem. Sci., 2024,15, 5944-5949
https://doi.org/10.1039/D4SC01173B
Investigation on the substrate specificity and N-substitution tolerance of PseF in catalytic transformation of pseudaminic acids to CMP-Pse derivatives
A series of synthetic pseudaminic acid analogues bearing different N5/N7 substitutions were transformed enzymatically into corresponding CMP-Pse species via PseF catalysis, which demonstrated the substrate promiscuity of PseF.
Chem. Sci., 2024,15, 5950-5956
https://doi.org/10.1039/D4SC00758A
The superiority of Pd2+ in CO2 hydrogenation to formic acid
The hydrogenation of CO2 to formic acid is catalyzed for the first time by a Pd2+ catalyst, Pd–V/AC–air. The superiority of Pd2+ over Pd0 is confirmed by a combination of DFT and experimental results.
Chem. Sci., 2024,15, 5525-5530
https://doi.org/10.1039/D3SC06925G
Investigating the diastereoselective synthesis of a macrocycle under Curtin–Hammett control
The Curtin–Hammett principle is used to understand the diastereoselective synthesis of a heterochiral over a homochiral macrocycle, both of which are configurationally stable chiral macrocycles.
Chem. Sci., 2024,15, 5516-5524
https://doi.org/10.1039/D3SC05715A
Cross-coupling of organic fluorides with allenes: a silyl-radical-relay pathway for the construction of α-alkynyl-substituted all-carbon quaternary centres
Cross-coupling of organic fluorides with allenes via radical rearrangement to afford all-carbon quaternary centres mediated by silylboronate/potassium tert-butoxide is disclosed.
Chem. Sci., 2024,15, 5113-5122
https://doi.org/10.1039/D3SC06617G
Phosphorescent acyclic cucurbituril solid supramolecular multicolour delayed fluorescence behaviour
Solid supramolecular phosphorescence between glycoluril derivatives and polyvinyl alcohol exhibited a green afterglow with a lifetime of 2.12 s, and a self-crimping configuration endows them with ability to encapsulate guests to achieve TS-FRET.
Chem. Sci., 2024,15, 5163-5173
https://doi.org/10.1039/D4SC00160E
Oxidation-induced ambiphilicity triggers N–N bond formation and dinitrogen release in octahedral terminal molybdenum(V) nitrido complexes
N–N bond formation in octahedral, terminal d1 Mo(V) nitridos to give μ-dinitrogen complexes requires one eletron oxidation with 0.5 equivalents of oxidant to open a kinetically feasible ambiphilic nitrido coupling pathway.
Chem. Sci., 2024,15, 5152-5162
https://doi.org/10.1039/D4SC00090K
IronIII-catalyzed asymmetric inverse-electron-demand hetero-Diels–Alder reaction of dioxopyrrolidines with simple olefins
A highly enantioselective [4 + 2] cycloaddition of a number of simple olefins with cyclic hetero-diene of dioxopyrrolidines is realized by a chiral iron(III)/N,N′-dioxide complex catalyst.
Chem. Sci., 2024,15, 4797-4803
https://doi.org/10.1039/D4SC00078A
Realizing highly efficient deep-blue organic light-emitting diodes towards Rec.2020 chromaticity by restricting the vibration of the molecular framework
A deep blue TADF emitter composed of rigid D and A units was developed. BOC-PSi-based OLED exhibited not only an impressive EQEmax approaching 20%, but also a superior color purity approaching the Rec.2020 blue standard.
Chem. Sci., 2024,15, 4790-4796
https://doi.org/10.1039/D3SC06763G
Delocalisation enables efficient charge generation in organic photovoltaics, even with little to no energetic offset
Simulations reveal that both charge and exciton delocalisation can significantly improve the efficiency of charge generation in organic photovoltaics and explain the failure of classical hopping approaches.
Chem. Sci., 2024,15, 4779-4789
https://doi.org/10.1039/D3SC05409H
s-Block metal complexes of superbulky (tBu3Si)2N−: a new weakly coordinating anion?
The extremely challenging deprotonation of the amine (tBu3Si)2NH led to a range of s-block metal complexes with superbulky (tBu3Si)2N−. Depending on metal and solvent, (tBu3Si)2N− can be classified as a halogen-free weakly coordinating anion.
Chem. Sci., 2024,15, 4386-4395
https://doi.org/10.1039/D3SC06896J
Halide-free synthesis of metastable graphitic BC3
A halide-free route to the synthesis of graphitic BC3 was discovered via decomposition temperature matching: benzene (C6H6) as the carbon precursor and the borohydride anion (BH4−) as the boron precursor.
Chem. Sci., 2024,15, 4358-4363
https://doi.org/10.1039/D3SC06837D
Site-directed cation ordering in chabazite-type AlxGa1−xPO4-34 frameworks revealed by NMR crystallography
NMR crystallography exposes preferential site ordering of Al and Ga in new mixed-metal phosphate frameworks.
Chem. Sci., 2024,15, 4374-4385
https://doi.org/10.1039/D3SC06924A
Mesoporous Mo-doped PtBi intermetallic metallene superstructures to enable the complete electrooxidation of ethylene glycol
Novel freestanding M-PtBiMo IMSs were achieved via a simple and effective one-step wet chemical method. The M-PtBiMo IMSs as highly efficient anode electrocatalysts boosted the activity and stability toward the EGOR and actual DEGFCs.
Chem. Sci., 2024,15, 4349-4357
https://doi.org/10.1039/D4SC00323C
Controllable π–π coupling of intramolecular dimer models in aggregated states
In situ regulation of π–π coupling was realized with the combination of rigid intramolecular dimer models and external stimuli, mainly due to the balance of π–π and solvent–π interactions. The results establish the quantitative relationship between emission properties and π–π distances.
Chem. Sci., 2024,15, 4364-4373
https://doi.org/10.1039/D3SC05533G
A covalent organic framework as a dual-active-center cathode for a high-performance aqueous zinc-ion battery
We designed a covalent organic framework (TA-PTO-COF) as a dual-active-center cathode. This work presents a promising organic cathode material for a high-performance aqueous zinc-ion battery.
Chem. Sci., 2024,15, 4341-4348
https://doi.org/10.1039/D3SC07013A
Photoswitchable imines: aryliminopyrazoles quantitatively convert to long-lived Z-isomers with visible light
Simple structural modifications significantly boost the photochromic performance of imine-based photoswitches. This work lays a foundation for exploring new motifs in light-addressable dynamic combinatorial chemistry.
Chem. Sci., 2024,15, 3872-3878
https://doi.org/10.1039/D3SC05841G
Discovery of antibacterial manganese(I) tricarbonyl complexes through combinatorial chemistry
To accelerate the discovery of novel metalloantibiotics we applied combinatorial synthesis to the preparation of 420 novel manganese tricarbonyl complexes.
Chem. Sci., 2024,15, 3907-3919
https://doi.org/10.1039/D3SC05326A
Multi-site isomerization of synergistically regulated stimuli-responsive AIE materials toward multi-level decryption
The utilization of multi-site modifications brings about the manipulation of excited-state processes and multi-stimuli responses of salicylaldehyde Schiff base isomers, which can be successfully applied in multi-level decryption.
Chem. Sci., 2024,15, 3920-3927
https://doi.org/10.1039/D3SC06191D
Organocatalytic enantioselective synthesis of Csp2–N atropisomers via formal Csp2–O bond amination
An organocatalyzed asymmetric synthesis of Csp2–N atropisomers by formal Csp2–O amination has been established from 3-alkynyl-3-hydroxyisoindolinones and 1-methylnaphthalen-2-ols.
Chem. Sci., 2024,15, 3893-3900
https://doi.org/10.1039/D3SC06707F
In situ SERS imaging of protein-specific glycan oxidation on living cells to quantitatively visualize pathogen–cell interactions
A SERS imaging strategy is developed to quantitatively visualize the protein-specific glycan oxidation mediated pathogen–cell interactions and pathogen-resistance mechanisms.
Chem. Sci., 2024,15, 3901-3906
https://doi.org/10.1039/D4SC00157E
Rare-earth metal ethylene and ethyne complexes
An unprecedented rare-earth ethyne complex is presented, and the α-H abstraction and C–C σ bond metathesis mechanism is proposed based on DFT calculations. The first example of a well-defined non-Cp rare-earth ethylene complex via the β-H abstraction reaction is also described herein.
Chem. Sci., 2024,15, 3495-3501
https://doi.org/10.1039/D3SC06599E
Iron(IV) alkyl complexes: electronic structure contributions to Fe–C bond homolysis and migration reactions that form N–C bonds from N2
Silylation of iron-alkyl-dinitrogen complexes gives high-spin iron(IV) products that also have an iron(II) resonance structure. The stability and reactivity of these compounds depends on the alkyl group, with insertion and homolysis observed.
Chem. Sci., 2024,15, 3485-3494
https://doi.org/10.1039/D3SC05939A
About this collection
This on-going web collection showcases all of the HOT Chemical Science articles published in 2024, as recommended by referees. Congratulations to all of the authors whose articles are featured.