Issue 95, 2018

Photostability of oxazoline RNA-precursors in UV-rich prebiotic environments

Abstract

Pentose aminooxazolines and oxazolidinone thiones are considered as the key precursors which could have enabled the formation of RNA nucleotides under the conditions of early Earth. UV-irradiation experiments and quantum-chemical calculations demonstrate that these compounds are remarkably photostable and could accumulate over long periods of time in UV-rich prebiotic environments to undergo stereoisomeric purification.

Graphical abstract: Photostability of oxazoline RNA-precursors in UV-rich prebiotic environments

Supplementary files

Article information

Article type
Communication
Submitted
10 Sept. 2018
Accepted
05 Nov. 2018
First published
09 Nov. 2018

Chem. Commun., 2018,54, 13407-13410

Photostability of oxazoline RNA-precursors in UV-rich prebiotic environments

M. J. Janicki, S. J. Roberts, J. Šponer, M. W. Powner, R. W. Góra and R. Szabla, Chem. Commun., 2018, 54, 13407 DOI: 10.1039/C8CC07343K

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