Issue 17, 2022

Cyrene: a bio-based novel and sustainable solvent for organic synthesis

Abstract

Dihydrolevoclucosenone (Cyrene is its market name) is a biomass-derived solvent that can be produced in only two steps from biomass, while being biodegradable, non-mutagenic and non-toxic. Its “green” profile combined with its physical properties makes Cyrene a plausible substitute for a number of widely used toxic organic solvents. The first attempt to assess Cyrene as a solvent dates back to 2014 and since then, numerous research groups have opted for this promising alternative. Cyrene has successfully been employed as a solvent in materials chemistry, peptide chemistry, organic synthesis and many more research fields, which are going to be discussed in the context of this review.

Graphical abstract: Cyrene: a bio-based novel and sustainable solvent for organic synthesis

Article information

Article type
Tutorial Review
Submitted
21 Jūn. 2022
Accepted
28 Jūl. 2022
First published
28 Jūl. 2022
This article is Open Access
Creative Commons BY-NC license

Green Chem., 2022,24, 6435-6449

Cyrene: a bio-based novel and sustainable solvent for organic synthesis

N. A. Stini, P. L. Gkizis and C. G. Kokotos, Green Chem., 2022, 24, 6435 DOI: 10.1039/D2GC02332F

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