Issue 10, 2012

A nanocrystal-based ratiometric pH sensor for natural pH ranges

Abstract

A ratiometric fluorescent pH sensor based on CdSe/CdZnS nanocrystal quantum dots (NCs) has been designed for biological pH ranges. The construct is formed from the conjugation of a pH dye (SNARF) to NCs coated with a poly(amido amine) (PAMAM) dendrimer. The sensor exhibits a well-resolved ratio response at pH values between 6 and 8 under linear or two-photon excitation, and in the presence of a 4% bovine serum albumin (BSA) solution.

Graphical abstract: A nanocrystal-based ratiometric pH sensor for natural pH ranges

Supplementary files

Article information

Article type
Edge Article
Submitted
21 Febr. 2012
Accepted
22 Jūn. 2012
First published
26 Jūn. 2012

Chem. Sci., 2012,3, 2980-2985

A nanocrystal-based ratiometric pH sensor for natural pH ranges

R. C. Somers, R. M. Lanning, P. T. Snee, A. B. Greytak, R. K. Jain, M. G. Bawendi and D. G. Nocera, Chem. Sci., 2012, 3, 2980 DOI: 10.1039/C2SC20212C

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