Issue 50, 2013

Locked nucleic acid: tighter is different

Abstract

This viewpoint briefly reviews the impact of Locked Nucleic Acid (LNA) oligonucleotides, first described in a ChemComm paper in 1998. A number of unique applications in oligonucleotide biotechnology have been made possible by the high binding affinity and specificity of LNA, and these provide the main focus of the viewpoint.

Graphical abstract: Locked nucleic acid: tighter is different

Article information

Article type
Viewpoint
Submitted
15 Janv. 2013
Accepted
10 Maijs 2013
First published
16 Maijs 2013

Chem. Commun., 2013,49, 5618-5620

Locked nucleic acid: tighter is different

J. K. Watts, Chem. Commun., 2013, 49, 5618 DOI: 10.1039/C3CC40340H

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements