Issue 31, 2021

Mechanism of Pd-catalysed C(sp3)–H arylation of thioethers with Ag(i) additives

Abstract

Mechanistic studies reveal that Pd-catalyzed C(sp3)–H arylation of thioethers with silver(I) additives takes place via C(sp3)–H activation, oxidative addition and reductive elimination, wherein all steps proceed via the heterodimeric Pd–Ag pathway. Besides, the active heterodimeric Pd–Ag species are detected by mass spectrometry via control experiments.

Graphical abstract: Mechanism of Pd-catalysed C(sp3)–H arylation of thioethers with Ag(i) additives

Supplementary files

Article information

Article type
Communication
Submitted
11 اپریل 2021
Accepted
14 جوٗلایی 2021
First published
14 جوٗلایی 2021

Org. Biomol. Chem., 2021,19, 6766-6770

Mechanism of Pd-catalysed C(sp3)–H arylation of thioethers with Ag(I) additives

W. Liu, Z. Liu, X. Liu and Y. Dang, Org. Biomol. Chem., 2021, 19, 6766 DOI: 10.1039/D1OB00704A

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements