Issue 22, 1989

Stereochemistry of reduction by the 5α-reductase enzyme of Penicillium decumbens and the 1H NMR assignment of 5α-dihydrotestosterone

Abstract

Reduction of the alkenic bond of testosterone and androst-4-ene-3,17-dione by the 5α-reductase enzyme of Penicillium decumbens proceeds with trans stereochemistry.

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1989, 1760-1761

Stereochemistry of reduction by the 5α-reductase enzyme of Penicillium decumbens and the 1H NMR assignment of 5α-dihydrotestosterone

H. L. Holland, W. Xu and D. W. Hughes, J. Chem. Soc., Chem. Commun., 1989, 1760 DOI: 10.1039/C39890001760

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