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The molecular “transformer”, oxatub[4]arene, was found to be able to host a wide range of organic cations. The strong binding ability is believed to originate from its four interconvertible and deep-cavity conformers. The binding behavior of such adaptable receptors may provide implications for molecular recognition in nature.

Graphical abstract: Oxatub[4]arene: a molecular “transformer” capable of hosting a wide range of organic cations

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