A 12-mer peptide with an affinity for the meso diad sequence of poly(N-isopropylacrylamide) (PNIPAM) was identified through affinity-based peptide screening. A model protein (i.e., human serum albumin (HSA)) chemically modified with the peptide was successfully precipitated with PNIPAM above the lower critical solution temperature (LCST) of PNIPAM.
S. Suzuki, T. Sawada, T. Ishizone and T. Serizawa, Chem. Commun., 2016, 52, 5670 DOI: 10.1039/C6CC00594B
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