Themed collection 2015 Journal of Materials Chemistry B Hot Papers
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High-density lipoproteins for therapeutic delivery systems
High-density lipoproteins are a class of natural nanostructures with multiple desirable properties to model in a drug delivery vehicle. Here we review the structure and function of high-density lipoproteins, and their use as therapeutic delivery systems.
J. Mater. Chem. B, 2016,4, 188-197
https://doi.org/10.1039/C5TB01332A
The evolution of fibrin-specific targeting strategies
A variety of antibodies, antibody fragments, and small peptides have been engineered to specifically target fibrin over its precursor fibrinogen.
J. Mater. Chem. B, 2015,3, 1177-1186
https://doi.org/10.1039/C4TB01769B
Biomolecular strategies to modulate the macrophage response to implanted materials
Materials engineered to display immunomodulatory molecules including adhesion ligands, cytokines, and self-proteins, target receptors on immune cells to modulate their response to biomaterial implants.
J. Mater. Chem. B, 2016,4, 1600-1609
https://doi.org/10.1039/C5TB01605C
Cellular modulation by the elasticity of biomaterials
The elasticity of the extracellular matrix has been increasingly recognized as a dominating factor of cell fate and activities. This review provides an overview of the general principles and recent advances in the field of matrix elasticity-dependent regulation of a variety of cellular activities and functions, the underlying biomechanical and molecular mechanisms, as well as the pathophysiological implications.
J. Mater. Chem. B, 2016,4, 9-26
https://doi.org/10.1039/C5TB02077H
Biomaterials for in situ tissue regeneration: development and perspectives
Biomaterials are of fundamental importance to in situ tissue regeneration, which has emerged as a powerful method to treat tissue defects. The development and perspectives of biomaterials for in situ tissue regeneration were summarized.
J. Mater. Chem. B, 2015,3, 8921-8938
https://doi.org/10.1039/C5TB01863C
Physical cues of cell culture materials lead the direction of differentiation lineages of pluripotent stem cells
Differentiation methods of hPSCs into specific cell lineages. Differentiation of hPSCs via EB formation (types AB, A–D) or without EB formation (types E–H).
J. Mater. Chem. B, 2015,3, 8032-8058
https://doi.org/10.1039/C5TB01276G
Hyaluronic acid and neural stem cells: implications for biomaterial design
While in the past hyaluronic acid (HA) was considered a passive structural component, research over the past few decades has revealed its diverse and complex biological functions resulting in a major ideological shift. This review describes recent advances in biological interactions of HA with neural stem cells, with a focus on leveraging these interactions to develop advanced biomaterials that aid regeneration of the central nervous system.
J. Mater. Chem. B, 2015,3, 7850-7866
https://doi.org/10.1039/C5TB00974J
The influence of polymer architecture on in vitro pDNA transfection
In the field of polymer-based gene delivery, the tuning potential of polymers by using different architectures like graft- and star-shaped polymers as well as self-assembled block copolymers is immense. In the last years numerous new polymer designs showed enhanced transfections properties in combination with a good biocompatibility.
J. Mater. Chem. B, 2015,3, 7477-7493
https://doi.org/10.1039/C5TB00782H
Understanding cell homing-based tissue regeneration from the perspective of materials
The triad of cell homing-based tissue engineering.
J. Mater. Chem. B, 2015,3, 7319-7333
https://doi.org/10.1039/C5TB01188D
The role of tissue engineering in cellular therapies for myocardial infarction: a review
Current medical treatments of myocardial infarction (MI) face a serious shortcoming in that they cannot reverse the detrimental effects of ischemia induced necrosis.
J. Mater. Chem. B, 2015,3, 6401-6410
https://doi.org/10.1039/C5TB00739A
Design of hybrid nanovehicles for remotely triggered drug release: an overview
This review addresses the advantages of remote triggers, e.g. ultrasounds, near infrared light and alternating magnetic fields, the fabrication of the hybrid nanovehicles, the release mechanisms and the next challenges.
J. Mater. Chem. B, 2015,3, 6117-6147
https://doi.org/10.1039/C5TB00664C
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The potential of nanoparticles for the immunization against viral infections
Vaccination has a great impact on the prevention and control of infectious diseases. Nanoparticles can deliver immunoactive biomolecules to induce a virus-specific immune response.
J. Mater. Chem. B, 2015,3, 4767-4779
https://doi.org/10.1039/C5TB00618J
An overview of the suitability of hydrogel-forming polymers for extrusion-based 3D-printing
In this review hydrogel-forming polymers that are suitable for extrusion-based 3D printing are evaluated.
J. Mater. Chem. B, 2015,3, 4105-4117
https://doi.org/10.1039/C5TB00393H
Fundamentals of double network hydrogels
Double network (DN) hydrogels as promising soft-and-tough materials intrinsically possess extraordinary mechanical strength and toughness due to their unique contrasting network structures, strong interpenetrating network entanglement, and efficient energy dissipation.
J. Mater. Chem. B, 2015,3, 3654-3676
https://doi.org/10.1039/C5TB00123D
Amelogenin and enamel biomimetics
Mature tooth enamel is acellular and does not regenerate itself.
J. Mater. Chem. B, 2015,3, 3112-3129
https://doi.org/10.1039/C5TB00163C
Rational design and applications of conducting polymer hydrogels as electrochemical biosensors
Conducting polymer hydrogels (CPHs) are conducting polymer-based materials that contain high water content and have physical properties, resembling the extracellular environment.
J. Mater. Chem. B, 2015,3, 2920-2930
https://doi.org/10.1039/C5TB00090D
Engineering and functionalization of biomaterials via surface modification
Recent progress pertaining to the surface treatment of implantable macro-scale biomaterials and using micro- and nano-biomaterials for disease diagnosis and drug/gene delivery is reviewed.
J. Mater. Chem. B, 2015,3, 2024-2042
https://doi.org/10.1039/C4TB01934B
Covalently cross-linked poly(2-oxazoline) materials for biomedical applications – from hydrogels to self-assembled and templated structures
We discuss covalently cross-linked poly(2-oxazoline)s including gels, nanogels and capsules on the basis of their synthetic origin in a biomedical context.
J. Mater. Chem. B, 2015,3, 526-538
https://doi.org/10.1039/C4TB01660B
Conversion of titania (TiO2) into conductive titanium (Ti) nanotube arrays for combined drug-delivery and electrical stimulation therapy
The conversion of titania (TiO2) nanotubes into titanium (Ti), while preserving their nanotubular structures is demonstrated for proposed application as bone implants and electrodes for combined local drug delivery and electrical stimulation therapy.
J. Mater. Chem. B, 2016,4, 371-375
https://doi.org/10.1039/C5TB02108A
Aggregation induced emission amphiphile with an ultra low critical micelle concentration: fabrication, self assembling, and cell imaging
An AIE-active amphiphile containing a tetraphenylethene moiety and a quarternary ammonium salt group, with an ultra low CMC, desirable optical properties, good water dispersibility and excellent biocompatibility, was prepared and investigated, and the as-prepared amphiphile was successfully applied in cell imaging.
J. Mater. Chem. B, 2016,4, 198-201
https://doi.org/10.1039/C5TB02462E
Spatially defined stem cell-laden hydrogel islands for directing endothelial tubulogenesis
Patterning of encapsulated MSCs for the spatio-temporal guidance of angiogenesis for modelling and design of therapeutic biomaterials.
J. Mater. Chem. B, 2015,3, 7896-7898
https://doi.org/10.1039/C5TB01294E
Virus-inspired mimics: self-assembly of dendritic lipopeptides into arginine-rich nanovectors for improving gene delivery
With inspirations from natural viruses, arginine-containing dendritic lipopeptides were designed for bioinspired fabrication.
J. Mater. Chem. B, 2015,3, 7006-7010
https://doi.org/10.1039/C5TB01070E
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A highly sensitive fluorescent light-up probe for real-time detection of the endogenous protein target and its antagonism in live cells
A target-specific switchable fluorescent probe for cellular Mdm2 protein detection (off–on) and drug discovery applications (on–off) targeting the p53 pathway.
J. Mater. Chem. B, 2015,3, 5933-5937
https://doi.org/10.1039/C5TB00819K
Revealing the direct effect of individual intercalations on DNA conductance toward single-molecule electrical biodetection
The effect of individual intercalations on DNA conductance is revealed electrically at the single-molecule level by using DNA-functionalized molecular junctions.
J. Mater. Chem. B, 2015,3, 5150-5154
https://doi.org/10.1039/C5TB00666J
Photostable AIE fluorogens for accurate and sensitive detection of S-phase DNA synthesis and cell proliferation
Two azide-functionalized AIE fluorogens are synthesized and used for detecting S-phase DNA synthesis and cell proliferation based on EdU assay.
J. Mater. Chem. B, 2015,3, 4993-4996
https://doi.org/10.1039/C5TB00458F
Rapid microwave-assisted synthesis of ultra-bright fluorescent carbon dots for live cell staining, cell-specific targeting and in vivo imaging
Ultra-bright fluorescent carbon dots were rapidly synthesized for multifunctional bio-imaging including live cell staining, cell-specific targeting and in vivo imaging.
J. Mater. Chem. B, 2015,3, 4786-4789
https://doi.org/10.1039/C5TB00570A
Modified chitosan emulsifiers: small compositional changes produce vastly different high internal phase emulsion types
By varying the oligolysine units of chitosan-graft-oligoNIPAM-graft-oligolysine, high internal phase emulsions of different droplet sizes can be stabilized which can subsequently serve as template for macroporous polymers.
J. Mater. Chem. B, 2015,3, 4118-4122
https://doi.org/10.1039/C5TB00303B
Highly stretchable and super tough nanocomposite physical hydrogels facilitated by the coupling of intermolecular hydrogen bonds and analogous chemical crosslinking of nanoparticles
Nanocomposite physical hydrogels fabricated by a one-step polymerization show ultra-extensibility and toughness due to an effective strengthening mechanism.
J. Mater. Chem. B, 2015,3, 1187-1192
https://doi.org/10.1039/C4TB01654H
Functional silsesquioxane-based hierarchical assemblies for antibacterial/antifungal coatings
This paper reports the first study on functional silsesquioxane-based hierarchical assemblies containing an ordered distribution of silver nanoparticles with a large number of {111} facets, obtained through sol–gel reaction, intended for antibacterial/antifungal coatings.
J. Mater. Chem. B, 2015,3, 723-727
https://doi.org/10.1039/C4TB01932F
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Carbon-based cores with polyglycerol shells – the importance of core flexibility for encapsulation of hydrophobic guests
Two core–shell nanoparticles with a polyglycerol shell and sp3 carbon core but different core flexibilities were synthesized and compared for their encapsulation capacities.
J. Mater. Chem. B, 2015,3, 719-722
https://doi.org/10.1039/C4TB01858C
Designing compartmentalized hydrogel microparticles for cell encapsulation and scalable 3D cell culture
Compartmentalized hydrogel microparticles with high production rate, uniform size and shape, and tunable ECM support were developed for various scalable 3D cell culture applications.
J. Mater. Chem. B, 2015,3, 353-360
https://doi.org/10.1039/C4TB01735H
The effect of PEGylation on the stimulation of IL-1β by gold (Au) nanoshell/silica core nanoparticles
PEGylation of Au nanoshell/silica core (GNS) particles reduces the aggregation in cell culture and the generation of IL-1β and the influx of neutrophils in the mouse peritoneal cavity.
J. Mater. Chem. B, 2016,4, 1650-1659
https://doi.org/10.1039/C5TB01553G
Surface micropatterning with zirconia and calcium phosphate ceramics by micromoulding in capillaries
Micropatterning of silicon surface with bioinert yttria-stabilised zirconia or bioactive calcium phosphate ceramic by micromoulding in capillaries.
J. Mater. Chem. B, 2016,4, 1044-1055
https://doi.org/10.1039/C5TB02027A
Electrospun fibers of chitosan-grafted polycaprolactone/poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) blends
CS-g-PCL/PHBHHx fiber blends show an optimal combination of strength, ductility, antibacterial activity and non-cytotoxicity, and thus are suitable as scaffolds for tissue engineering.
J. Mater. Chem. B, 2016,4, 600-612
https://doi.org/10.1039/C5TB01861G
Lipid micelles packaged with semiconducting polymer dots as simultaneous MRI/photoacoustic imaging and photodynamic/photothermal dual-modal therapeutic agents for liver cancer
Semiconducting polymer dot micelles for MRI/photoacoustic imaging and single-laser-induced PDT/PTT therapy.
J. Mater. Chem. B, 2016,4, 589-599
https://doi.org/10.1039/C5TB01827G
Investigating the potential of human placenta-derived extracellular matrix sponges coupled with amniotic membrane-derived stem cells for osteochondral tissue engineering
Placental extracellular matrix for osteochondral defects.
J. Mater. Chem. B, 2016,4, 613-625
https://doi.org/10.1039/C5TB02321A
In vitro degradation and angiogenesis of the porous calcium silicate–gelatin composite scaffold
Calcium silicate-gelatin scaffolds stimulated the release of angiogenesis factors such as von Willebrand factor and angiopoietin-1 more than the calcium silicate scaffold.
J. Mater. Chem. B, 2016,4, 505-512
https://doi.org/10.1039/C5TB02401C
Different chemical strategies to aminate oxidised multi-walled carbon nanotubes for siRNA complexation and delivery
The carboxylic groups of oxidised multi-walled carbon nanotubes were directly converted into amino functions without extending the lateral chain. These nanotubes have been investigated as carriers for siRNA delivery.
J. Mater. Chem. B, 2016,4, 431-441
https://doi.org/10.1039/C5TB02088C
Light-sensitive ruthenium complex-loaded cross-linked polymeric nanoassemblies for the treatment of cancer
Cross-linked polymeric nanoassemblies are potential carrier systems for cytotoxic ruthenium complexes, and exhibit a combination of electrostatic and hydrophobic interactions with the metal complexes that impact release rates, release percentages, and biological activity.
J. Mater. Chem. B, 2016,4, 394-408
https://doi.org/10.1039/C5TB01613D
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High biocompatibility and improved osteogenic potential of amorphous calcium carbonate/vaterite
Metastable amorphous calcium carbonate (ACC), formed as a precursor of crystalline carbonated apatite/hydroxyapatite in human bone, can be stabilized by inorganic polyphosphate. The resulting CaCO3/polyP, containing small amounts of vaterite, has osteogenic potential and potential application as a scaffold material for bone implants.
J. Mater. Chem. B, 2016,4, 376-386
https://doi.org/10.1039/C5TB02228B
Understanding the contribution of surface roughness and hydrophobic modification of silica nanoparticles to enhanced therapeutic protein delivery
The contribution of the surface roughness and hydrophobic modification of silica nanoparticles to enhanced therapeutic protein delivery, including adsorption, sustained release, cellular uptake and endo/lysosomal escape.
J. Mater. Chem. B, 2016,4, 212-219
https://doi.org/10.1039/C5TB01911G
Regulating the stemness of mesenchymal stem cells by tuning micropattern features
The stemness of MSCs was significantly influenced by cell morphogenesis regulated by micropatterns, and was always accompanied with change of nuclear activity and cytoskeleton mediated nanomechanics.
J. Mater. Chem. B, 2016,4, 37-45
https://doi.org/10.1039/C5TB02215K
Synthesis and characterization of waterborne polyurethane containing poly(3-hydroxybutyrate) as new biodegradable elastomers
Poly(3-hydroxybutyrate) (PHB) is a biodegradable polymer with good biocompatibility.
J. Mater. Chem. B, 2015,3, 9089-9097
https://doi.org/10.1039/C5TB01773D
An acid-free microwave approach to prepare highly luminescent boron-doped graphene quantum dots for cell imaging
Highly luminescent graphene quantum dots (GQDs) are obtained by restoring the defects of GQDs via incorporation of B atoms into the graphene framework, which exhibits great potential in bio-imaging.
J. Mater. Chem. B, 2015,3, 9109-9114
https://doi.org/10.1039/C5TB01954K
A versatile pH-responsive platform for intracellular protein delivery using calcium phosphate nanoparticles
A highly biocompatible nanoplatform for the intracellular delivery of different proteins, exhibiting pH-responsive release and efficient endosomal escape.
J. Mater. Chem. B, 2015,3, 9115-9121
https://doi.org/10.1039/C5TB01760B
Facile synthesis of hyaluronic acid-modified Fe3O4/Au composite nanoparticles for targeted dual mode MR/CT imaging of tumors
Hyaluronic acid-modified Fe3O4/Au composite nanoparticles can be synthesized for targeted dual mode MR/CT imaging of tumors.
J. Mater. Chem. B, 2015,3, 9098-9108
https://doi.org/10.1039/C5TB02040A
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Zinc-imidazolate polymers (ZIPs) as a potential carrier to brain capillary endothelial cells
Herein, we report the synthesis and characterization of nanospheres of a biodegradable zinc-imidazolate polymers (ZIPs) as a proof-of-concept delivery vehicle into human brain endothelial cells, the main component of the blood-brain barrier (BBB).
J. Mater. Chem. B, 2015,3, 9053-9059
https://doi.org/10.1039/C5TB01814E
Good hydration and cell-biological performances of superparamagnetic calcium phosphate cement with concentration-dependent osteogenesis and angiogenesis induced by ferric iron
Superparamagnetic Fe3+-doped calcium phosphate cement (Fe-CPC) has prospective applications in bone remodeling due to its good hydration properties and significant effect on osteogenesis and angiogenesis.
J. Mater. Chem. B, 2015,3, 8782-8795
https://doi.org/10.1039/C5TB01440A
Heparin-based temperature-sensitive injectable hydrogels for protein delivery
Polysaccharide-based biodegradable, biocompatible and temperature-sensitive injectable hydrogels have been developed for the sustained delivery of proteins.
J. Mater. Chem. B, 2015,3, 8892-8901
https://doi.org/10.1039/C5TB01399B
Novel protein-loaded chondroitin sulfate-N-[(2-hydroxy-3-trimethylammonium)propyl]chitosan nanoparticles with reverse zeta potential: preparation, characterization, and ex vivo assessment
Positively and negatively surface charged nanoparticles were prepared by a facile PEC method composed of chondroitin sulfate and N-[(2-hydroxy-3-trimethylammonium)propyl]chitosan.
J. Mater. Chem. B, 2015,3, 8729-8737
https://doi.org/10.1039/C5TB01517K
Effect of direct loading of phytoestrogens into the calcium phosphate scaffold on osteoporotic bone tissue regeneration
3D porous calcium deficient hydroxyapatite scaffolds with phytoestrogens were fabricated for osteoporotic bone tissue regeneration through a combination of 3D printing techniques and cement chemistry as a room temperature process.
J. Mater. Chem. B, 2015,3, 8694-8703
https://doi.org/10.1039/C5TB01574J
Prevention of surface-induced thrombogenesis on poly(vinyl chloride)
PVC is derivatized with an ultrathin MEG coating with remarkable antithrombogenicity. Assessed upon exposure to fluorescently-labelled human blood, at various shear rates and contact periods, platelet aggregation/clotting coverage is reduced by >95–99% for coated vs. bare PVC surfaces.
J. Mater. Chem. B, 2015,3, 8623-8628
https://doi.org/10.1039/C5TB01582K
Surface coatings with covalently attached caspofungin are effective in eliminating fungal pathogens
In this work we have prepared surface coatings formulated with the antifungal drug caspofungin, an approved pharmaceutical lipopeptide compound of the echinocandin drug class.
J. Mater. Chem. B, 2015,3, 8469-8476
https://doi.org/10.1039/C5TB00961H
Single component thermo-gelling electroactive hydrogels from poly(caprolactone)–poly(ethylene glycol)–poly(caprolactone)-graft-aniline tetramer amphiphilic copolymers
Single component injectable degradable conductive hydrogels with excellent biocompatibility based on poly(caprolactone)–poly(ethylene glycol)–poly(caprolactone) and aniline tetramer were prepared via a thermo-gelling approach.
J. Mater. Chem. B, 2015,3, 8459-8468
https://doi.org/10.1039/C5TB01658D
Design of a versatile nanocomposite for ‘seeing’ drug release and action behavior
To design a new method for ‘seeing’ drug release and action behavior, we combined a rare-earth complex with a magnetic-core-coated phenyl mesoporous silica nanoparticles matrix, taking advantage of the drug coordination for real-time monitoring.
J. Mater. Chem. B, 2015,3, 8449-8458
https://doi.org/10.1039/C5TB01367D
In vitro biocompatibility of mesoporous metal (III; Fe, Al, Cr) trimesate MOF nanocarriers
The high porosity and versatile composition of the benchmarked mesoporous metal (Fe, Al, Cr) trimesate metal–organic frameworks (MIL-100(Fe, Al, Cr)) make them very promising solids in different strategic industrial and societal domains (separation, catalysis, biomedicine, etc.).
J. Mater. Chem. B, 2015,3, 8279-8292
https://doi.org/10.1039/C5TB01223F
Plasmon-induced hyperthermia: hybrid upconversion NaYF4:Yb/Er and gold nanomaterials for oral cancer photothermal therapy
Bi-functional nanocomposites consisting of upconversion nanoparticles and gold nanoparticles or gold nanorods are fabricated for oral cancer cell photothermal therapy.
J. Mater. Chem. B, 2015,3, 8293-8302
https://doi.org/10.1039/C5TB01393C
Facile synthesis of yolk–shell silica nanoparticles for targeted tumor therapy
Redox-responsive yolk–shell silica nanoparticles end-capped with rotaxane nanovalves were fabricated for targeted tumor therapy with high efficiency.
J. Mater. Chem. B, 2015,3, 8303-8313
https://doi.org/10.1039/C5TB01620G
Bioengineered mussel glue incorporated with a cell recognition motif as an osteostimulating bone adhesive for titanium implants
An engineered mussel glue MAP-RGD can be successfully used as a novel functional osteostimulating bone adhesive for titanium implants through improved osteoblastic cell behaviors, blood responses, and eventually enhanced bone regeneration.
J. Mater. Chem. B, 2015,3, 8102-8114
https://doi.org/10.1039/C5TB01230A
Multifunctional REDV-conjugated zwitterionic polycarboxybetaine–polycaprolactone hybrid surfaces for enhanced antibacterial activity, anti-thrombogenicity and endothelial cell proliferation
Multifunctional PCL hybrid surfaces are developed by grafting of REDV–zwitterionic polycarboxybetaine conjugates via surface-initiated ATRP.
J. Mater. Chem. B, 2015,3, 8088-8101
https://doi.org/10.1039/C5TB01598G
pH-Sensitive pullulan–DOX conjugate nanoparticles for co-loading PDTC to suppress growth and chemoresistance of hepatocellular carcinoma
Co-delivery of DOX and PDTC using pH-sensitive pullulan–DOX conjugate nanoparticles helped to suppress growth and chemoresistance of hepatocellular carcinoma.
J. Mater. Chem. B, 2015,3, 8070-8078
https://doi.org/10.1039/C5TB01210D
Swim bladder collagen forms hydrogel with macroscopic superstructure by diffusion induced fast gelation
Type I collagen extracted from the swim bladder of Bester sturgeon forms an oriented hydrogel with mechanical and thermal stability by diffusion induced fast gelation.
J. Mater. Chem. B, 2015,3, 7658-7666
https://doi.org/10.1039/C5TB00877H
Vesicle-like nanospheres of amorphous calcium phosphate: sonochemical synthesis using the adenosine 5′-triphosphate disodium salt and their application in pH-responsive drug delivery
Amorphous calcium phosphate vesicle-like nanospheres synthesized sonochemically using ATP can be used as pH-responsive drug nanocarriers.
J. Mater. Chem. B, 2015,3, 7347-7354
https://doi.org/10.1039/C5TB01340B
Multiple noncovalent interactions mediated one-pot therapeutic assemblies for the effective treatment of atherosclerosis
Therapeutic microspheres are engineered by multiple noncovalent interactions mediated one-pot assembly, which may serve as effective and safe therapeutics for atherosclerosis.
J. Mater. Chem. B, 2015,3, 7355-7365
https://doi.org/10.1039/C5TB01474C
Narrow band gap conjugated polyelectrolytes for photothermal killing of bacteria
We report the demonstration of antimicrobial conjugated polyelectrolytes (CPEs) with high NIR absorbance for selective and efficient photothermal killing of bacteria over mammalian cells.
J. Mater. Chem. B, 2015,3, 7340-7346
https://doi.org/10.1039/C5TB01118C
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Gene silencing of the pro-inflammatory cytokine TNF-α with siRNA delivered by calcium phosphate nanoparticles, quantified by different methods
The expression of the proinflammatory cytokine TNF-α was efficiently downregulated with nanoparticles, opening a way to combat inflammatory reactions.
J. Mater. Chem. B, 2015,3, 7186-7193
https://doi.org/10.1039/C5TB01377A
New imaging reagents for lipid dense regions in live cells and the nucleus in fixed MCF-7 cells
Specific imaging of lipid dense regions of live MCF-7 cells is achieved with two new Ru(II)-polypyridyl complexes 1 and 2. These visible light excitable reagents are stable towards photo-bleaching and large Stokes shifts are observed. Interestingly, these reagents were localized in the cell nucleus in PFA fixed MCF-7 cells.
J. Mater. Chem. B, 2015,3, 7177-7185
https://doi.org/10.1039/C5TB01309G
A zinc complex of a neutral pyridine-based amphiphile: a highly efficient and potentially therapeutic bactericidal material
The complexation of Zn(II) with a neutral pyridine-based amphiphile generates a potent bactericidal material for potential antibacterial and antibiofilm therapy.
J. Mater. Chem. B, 2015,3, 7068-7078
https://doi.org/10.1039/C5TB01259G
Boron ketoiminate-based conjugated polymers with tunable AIE behaviours and their applications for cell imaging
A series of AIE-active D–A type conjugated polymers incorporating boron ketoiminate units were synthesized and applied for cell imaging.
J. Mater. Chem. B, 2015,3, 7030-7036
https://doi.org/10.1039/C5TB01262G
Ultra-bright near-infrared-emitting HgS/ZnS core/shell nanocrystals for in vitro and in vivo imaging
Novel ultra-bright, stable NIR-emitting HgS/ZnS core/shell NCs with good biocompatibility for in vitro and in vivo imaging.
J. Mater. Chem. B, 2015,3, 6928-6938
https://doi.org/10.1039/C5TB01034A
About this collection
This on-going web collection features all the articles published in Journal of Materials Chemistry B in 2015 marked as HOT, as recommended by referees. Congratulations to all the authors whose articles are featured!