Themed collection Chemistry for Medicine: Special Collection for RSC Advances

This article reviews antibacterial surface strategies based on reactive plasma chemistry, focusing on how plasma-assisted processing of natural antimicrobial agents can produce antifouling and antibacterial materials for biomedical devices.

This review article summarizes the latest progress in research regarding bioapplications of graphene oxide derivatives and provides expert opinions on strategies for overcoming the current challenges.

Metal-free domino one-pot protocols for quinoline synthesis have been reviewed.

This article reviews recent advances in the crosslinking chemistries of biomimetic hydrogels prepared from PEG-based macromers.

This review article summarizes the recent progress on surface plasmon-enhanced light harvesting and its applications toward enhanced photocatalysis, photodynamic therapy, chemical transformations and photovoltaics.

Oxidative stress, a result of an overproduction and accumulation of free radicals, is the leading cause of several degenerative diseases such as cancer, atherosclerosis, cardiovascular diseases, ageing and inflammatory diseases.

This review describes hydrogels and their classifications along with the synthesis and properties of biopolymer-dextrin based crosslinked hydrogels towards potential application in controlled drug delivery.

A review of the role that nanoparticles can play in point-of-care diagnostics that utilize consumer electronic devices such as cell phones and smartphones for readout, including an overview of important concepts and examples from the literature.

Graphene quantum dots with unique properties have great potential applications for biosensing and bioimaging.

Naphthoquinone moieties are present in drugs such as doxorubicin which are used clinically to treat solid cancers.

This review discusses the recent developments on biological and pharmacological activities of amaryllidaceae alkaloids with IC₅₀ or EC₅₀ values since 2005, supporting the potential therapeutic possibilities for the use of these compounds.

Pyrrole is widely known as a biologically active scaffold which possesses a diverse nature of activities.

Recent advances in characterizing ultrasmall thiolated Ag nanoclusters, showing their optical and biological properties, and size, composition, and structure information.

This review covers the synthesis of achiral diarylmethanols, diaryl and triarylmethanes and the bioactivities of diaryl and triarylmethanes during 1995 to 2013.

Herein, we review the bioimaging application of three kinds of fluorescent carbon dots (CDs), namely, graphene quantum dots (GQDs), carbon nanodots (CNDs) and polymer dots (PDs).

This review article gives information about the recent advances in the synthesis of quinoline derivatives by various eco-friendly, green and clean protocols.

This review highlights and addresses issues related to research on the development of mesoporous silica nanomaterials (MSNs) based nanodevices for biological applications.

Recent research activities on the surface modification and biomedical applications of TiO₂ NTAs are reviewed.

Though much progress has been made in drug delivery systems, the design of a suitable carrier for the delivery of hydrophobic drugs is still a major challenge for researchers.

Nucleic acid based therapeutics comprising chemically modified oligonucleotides are the current focus of clinical research for the treatment of various diseases.

This review considers the importance of surface modifications of mesoporous nanoparticles and their biological consequences.

On recent advances in the development of carbon-based quantum dots, carbon dots in particular, for fluorescence imaging of cells and tissues.

The chemical properties of curcumin as well as its proposed mechanism of action as an anti-cancer therapeutic are reviewed. Recent approaches to curcumin delivery are described.

Dual-functionality carbon dots with both anti-microbial and gene transfection abilities were developed and their properties elaborated in this paper.

We describe in this work the synthesis of microparticles with a doxorubicin drug conjugated alginate core and a shell of peptide amphiphile nanofibres functionalized for targeting the folate receptor.

Curcumin encapsulated mesoporous silica nanoparticle (MSN) displaying higher cytotoxic for treatment in skin cancer cell line compared to pure curcumin.

This work represents the first time that poly(PEG/PPG/PLA urethane) has been used for the delivery of drugs to tumours in vivo and the encouraging results point to the potential for further development of this thermogel platform for anti-cancer applications.

Highly active antibacterial poly(N,N-dimethylaminoethyl methacrylate)-block-poly(L-lactic acid)-block-poly(N,N-dimethylaminoethyl methacrylate) conjugated with poly(ethylene glycol) (D-PLLA-D@PEG) copolymers were synthesized.

The loop sequences in i-motif DNA templates are well correlated with the fluorescence of the prepared Ag clusters.

Fabrication of two novel three-dimensional, conducting, biocompatible, porous, and elastic scaffolds composed of hyperbranched aliphatic polyesters, polyaniline, and poly(ε-caprolactone) for tissue engineering applications.

A new cellulose-based nanocomposite was synthesized, characterization and used for the synthesis of imidazoles and α-aminonitriles, and antibacterial property was investigated.

Effective physiological bone integration and absence of bacterial infection are essential for a successful orthopaedic or dental implant.

A continuous concentric impinging stream method was used for preparing ZnO/Ag MNSs, which possessed excellent photocatalytic and antibacterial activities.

The interaction of graphene with spermatozoa resulted in trapping, oxidative stress, mitochondria damage, DNA damage and finally death of the spermatozoa.

Schematic representation of the synthetic strategy for TiO₂/Ag₃PO₄/GR composites.

Synthesis of chitosan–aniline tetramer and its electroactive nanofibrous scaffolds enhanced cell adhesion and proliferation of C2C12 myoblasts.

Facile encapsulation of aggregation-induced emission dye into silica nanoparticles via a modified Stöber method was developed. Cell imaging applications of such luminescent silica nanoparticles were further investigated.

Size-specific antibacterial activity of 5–100 nm silver nanoparticles synthesized using a novel co-reduction approach.

PVDF film was functionalized by grafting of RGD-click-poly(glycidyl methacrylate) brushes using the combination of direct surface-initiated ATRP and alkyne-azide click reaction for improved cell adhesion and proliferation.