Issue 33, 2011

Photodimerisation of glycothymidines in solution and in micelles

Abstract

Glycothymidines were designed and synthesized as a new class of functional glycomimetics in which a photochemical [2+2] cycloaddition of the thymine moiety induces structural changes of carbohydrate presentation. To test if photodimerisation of these glycothymidines is feasible within an array of molecules, the photochemical reaction was investigated using NMR and NMR diffusion experiments in solution as well as in the supramolecular context of detergent micelles that mimic cellular membranes.

Graphical abstract: Photodimerisation of glycothymidines in solution and in micelles

Supplementary files

Article information

Article type
Communication
Submitted
01 Мау. 2011
Accepted
28 Мау. 2011
First published
19 Шіл. 2011

Chem. Commun., 2011,47, 9399-9401

Photodimerisation of glycothymidines in solution and in micelles

K. Schwekendiek, H. Kobarg, L. Daumlechner, F. D. Sönnichsen and T. K. Lindhorst, Chem. Commun., 2011, 47, 9399 DOI: 10.1039/C1CC13246F

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements