Cationic gold(I)-catalyzed enantioselective hydroalkylation of unactivated alkenes: influence of the chloride scavenger on the stereoselectivity

Weizhen Fang; Marc Presset; Amandine Guérinot; Christophe Bour; Sophie Bezzenine-Lafollée; Vincent Gandon

doi:10.1039/C4QO00112E

You do not have JavaScript enabled. Please enable JavaScript to access the full features of the site or access our non-JavaScript page.

Cationic gold(i)-catalyzed enantioselective hydroalkylation of unactivated alkenes: influence of the chloride scavenger on the stereoselectivity†

Weizhen Fang,^a Marc Presset,^a Amandine Guérinot,^a Christophe Bour,^a Sophie Bezzenine-Lafollée*^a and Vincent Gandon*^a

Author affiliations

* Corresponding authors

^a ICMMO (UMR CNRS 8182), LabEx CHARMMMAT, Université Paris-Sud, 91405 Orsay, France
E-mail: vincent.gandon@u-psud.fr
Fax: (+)33 169 154 747
Tel: (+)33 169 153 931

Abstract

Enantioselective intramolecular additions of β-ketoamides to unactivated alkenes have been accomplished by means of gold catalysis. Chiral LAuCl complexes have been activated by various Lewis acids (Cu, Ag, Ga, In, Si, Bi etc.). The influence of these activators on the stereoselectivity has been studied.

This article is part of the themed collection: In Celebration of Max Malacria’s 65th Birthday

Download options Please wait...

Supplementary files

Supplementary information PDF (8990K)

Article information

DOI: https://doi.org/10.1039/C4QO00112E
Article type: Research Article
Submitted: 17 Сәу. 2014
Accepted: 30 Сәу. 2014
First published: 05 Мам. 2014

Download Citation

Org. Chem. Front., 2014,1, 608-613

Permissions

Request permissions

Cationic gold(I)-catalyzed enantioselective hydroalkylation of unactivated alkenes: influence of the chloride scavenger on the stereoselectivity

W. Fang, M. Presset, A. Guérinot, C. Bour, S. Bezzenine-Lafollée and V. Gandon, Org. Chem. Front., 2014, 1, 608 DOI: 10.1039/C4QO00112E

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Social activity

Fetching data from CrossRef.
This may take some time to load.

Organic Chemistry Frontiers

Cationic gold(i)-catalyzed enantioselective hydroalkylation of unactivated alkenes: influence of the chloride scavenger on the stereoselectivity†

Abstract

Supplementary files

Article information

Download Citation

Permissions

Cationic gold(I)-catalyzed enantioselective hydroalkylation of unactivated alkenes: influence of the chloride scavenger on the stereoselectivity

Social activity

Search articles by author

Spotlight

Advertisements