Issue 52, 2014

Diastereoselective allylation and crotylation of N-tert-butanesulfinyl imines with allylic alcohols

Abstract

The palladium-catalyzed allylation of N-tert-butanesulfinyl imines with allylic alcohols in the presence of InI as reducing reagent takes place with high diastereoselectivity in reasonable yields. The reaction with crotyl alcohol is totally regioselective, leading to the anti-diastereomer as the main reaction product.

Graphical abstract: Diastereoselective allylation and crotylation of N-tert-butanesulfinyl imines with allylic alcohols

Supplementary files

Article information

Article type
Communication
Submitted
28 3 2014
Accepted
23 4 2014
First published
24 4 2014
This article is Open Access
Creative Commons BY license

Chem. Commun., 2014,50, 6898-6901

Author version available

Diastereoselective allylation and crotylation of N-tert-butanesulfinyl imines with allylic alcohols

O. S. D. R. Barros, J. A. Sirvent, F. Foubelo and M. Yus, Chem. Commun., 2014, 50, 6898 DOI: 10.1039/C4CC02317J

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