Issue 26, 2009

Nickel/AlMe2Cl-catalysed carbocyanation of alkynes using arylacetonitriles

Abstract

Nickel/Lewis acid dual catalysis was found to effect the carbocyanation reaction of alkynes using arylacetonitriles, giving a range of triply substituted acrylonitriles; the reaction of optically active α-phenylpropionitrile suggested a reaction mechanism that involves oxidative addition of a C–CN bond with retention of its absolute configuration.

Graphical abstract: Nickel/AlMe2Cl-catalysed carbocyanation of alkynes using arylacetonitriles

Supplementary files

Article information

Article type
Communication
Submitted
14 4 2009
Accepted
05 5 2009
First published
26 5 2009

Chem. Commun., 2009, 3931-3933

Nickel/AlMe2Cl-catalysed carbocyanation of alkynes using arylacetonitriles

A. Yada, T. Yukawa, Y. Nakao and T. Hiyama, Chem. Commun., 2009, 3931 DOI: 10.1039/B907290J

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements