Issue 56, 2023

An electrochemical cascade process: synthesis of 3-selenylindoles from 2-alkynylanilines with diselenides

Abstract

Substituted organoselenium compounds are crucial structural motifs in pharmaceutical molecules. Herein, we report a metal, oxidant, and base-free electrochemical approach to access 3-selenylindoles through an oxidative cyclization of 2-alkynylanilines with diselenides. This environmentally friendly approach demonstrates a wide range of substrate scope under mild reaction conditions in an electrochemical undivided cell setup.

Graphical abstract: An electrochemical cascade process: synthesis of 3-selenylindoles from 2-alkynylanilines with diselenides

Supplementary files

Article information

Article type
Communication
Submitted
11 5 2023
Accepted
18 6 2023
First published
19 6 2023

Chem. Commun., 2023,59, 8719-8722

An electrochemical cascade process: synthesis of 3-selenylindoles from 2-alkynylanilines with diselenides

A. B. Dapkekar and G. Satyanarayana, Chem. Commun., 2023, 59, 8719 DOI: 10.1039/D3CC02294C

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements