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Issue 40, 2015
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Spatially defined stem cell-laden hydrogel islands for directing endothelial tubulogenesis

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Abstract

The spatiotemporal coordination of angiogenesis in synthetic materials is important for mimicking natural tissue morphogenesis. Here we report patterned hydrogel encapsulation of mesenchymal stem cells to direct endothelial tubulogenesis in co-culture. Tubulogenesis occurs preferentially over MSC patterns, suggesting this strategy may prove useful in guiding the design of heterotypic engineered tissues.

Graphical abstract: Spatially defined stem cell-laden hydrogel islands for directing endothelial tubulogenesis

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Article information


Submitted
30 jún. 2015
Accepted
06 ágú. 2015
First published
06 ágú. 2015

J. Mater. Chem. B, 2015,3, 7896-7898
Article type
Communication

Spatially defined stem cell-laden hydrogel islands for directing endothelial tubulogenesis

A. A. Abdeen, J. Lee, S. H. Mo and K. A. Kilian, J. Mater. Chem. B, 2015, 3, 7896
DOI: 10.1039/C5TB01294E

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