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Issue 40, 2015
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Spatially defined stem cell-laden hydrogel islands for directing endothelial tubulogenesis

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Abstract

The spatiotemporal coordination of angiogenesis in synthetic materials is important for mimicking natural tissue morphogenesis. Here we report patterned hydrogel encapsulation of mesenchymal stem cells to direct endothelial tubulogenesis in co-culture. Tubulogenesis occurs preferentially over MSC patterns, suggesting this strategy may prove useful in guiding the design of heterotypic engineered tissues.

Graphical abstract: Spatially defined stem cell-laden hydrogel islands for directing endothelial tubulogenesis

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Publication details

The article was received on 30 jún. 2015, accepted on 06 ágú. 2015 and first published on 06 ágú. 2015


Article type: Communication
DOI: 10.1039/C5TB01294E
Citation: J. Mater. Chem. B, 2015,3, 7896-7898

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    Spatially defined stem cell-laden hydrogel islands for directing endothelial tubulogenesis

    A. A. Abdeen, J. Lee, S. H. Mo and K. A. Kilian, J. Mater. Chem. B, 2015, 3, 7896
    DOI: 10.1039/C5TB01294E

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