Issue 25, 2023

A fluorescent probe based on an enhanced ICT effect for Hg2+ detection and cell imaging

Abstract

The mercury ion (Hg2+) has hindered society to some extent due to its high biological toxicity, and a rapid method for Hg2+ detection is urgently needed. In the present work, two fluorescent probes, YF-Hg and YF-Cl-Hg, were developed. YF-Cl-Hg was produced by introducing an electron-withdrawing substituent (–Cl) into the structure of YF-Hg. The probe YF-Cl-Hg possesses a larger Stokes shift and a more pronounced UV-vis absorption redshift compared to YF-Hg in a pH = 7.4 environment. The reasons for the superior spectral performance of YF-Cl-Hg over YF-Hg were explored by density functional theory (DFT) calculations and UV-vis absorption spectroscopy. Furthermore, the good biocompatibility suggests that YF-Cl-Hg possesses the potential to be a tool for Hg2+ detection in cells.

Graphical abstract: A fluorescent probe based on an enhanced ICT effect for Hg2+ detection and cell imaging

Supplementary files

Article information

Article type
Paper
Submitted
11 अप्रैल 2023
Accepted
23 मई 2023
First published
23 मई 2023

Anal. Methods, 2023,15, 3026-3033

A fluorescent probe based on an enhanced ICT effect for Hg2+ detection and cell imaging

S. Pei, C. Li, X. Pei, X. Zhang, Y. Chi, W. Zeng, Y. Zhang, X. Liao and J. Chen, Anal. Methods, 2023, 15, 3026 DOI: 10.1039/D3AY00544E

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements