Issue 4, 2015

Cleavage of the C–C triple bond of ketoalkynes: synthesis of 4(3H)-quinazolinones

Abstract

A novel protocol for the synthesis of 4(3H)-quinazolinones via selective cleavage of the triple bond of ketoalkynes under oxidant-, metal-, and ligand-free conditions has been developed. Various 4(3H)-quinazolinones were obtained through fragmentation of the C–C triple bond and formation of two C–N bonds.

Graphical abstract: Cleavage of the C–C triple bond of ketoalkynes: synthesis of 4(3H)-quinazolinones

Supplementary files

Article information

Article type
Research Article
Submitted
05 अक्तूबर 2014
Accepted
09 फरवरी 2015
First published
11 फरवरी 2015

Org. Chem. Front., 2015,2, 366-368

Author version available

Cleavage of the C–C triple bond of ketoalkynes: synthesis of 4(3H)-quinazolinones

X. Yang, G. Cheng, J. Shen, C. Kuai and X. Cui, Org. Chem. Front., 2015, 2, 366 DOI: 10.1039/C4QO00260A

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements