Issue 22, 2023

Synthesis of functionalized sulfilimines via iron-catalyzed sulfur alkylation of sulfenamides with diazo compounds

Abstract

An efficient iron-catalyzed sulfur alkylation of sulfenamides with 2,2,2-trifluorodiazoethane is developed. The reaction proceeds smoothly at room temperature in an open flask, enabling the rapid synthesis of trifluoromethylated sulfilimines in moderate to good yields with broad functional group tolerance. In addition, this operationally simple protocol could also be applied to access cyano- and phosphonyl-functionalized sulfilimines using diazoacetonitrile or diazomethylphosphonate.

Graphical abstract: Synthesis of functionalized sulfilimines via iron-catalyzed sulfur alkylation of sulfenamides with diazo compounds

Supplementary files

Article information

Article type
Communication
Submitted
19 ספט 2023
Accepted
23 אוק 2023
First published
23 אוק 2023

Green Chem., 2023,25, 9092-9096

Synthesis of functionalized sulfilimines via iron-catalyzed sulfur alkylation of sulfenamides with diazo compounds

X. Wu, M. Chen, F. He and J. Wu, Green Chem., 2023, 25, 9092 DOI: 10.1039/D3GC03528J

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements