Issue 3, 2013
From the journal:

Chemical Communications

RNA-templated molecule release induced protein expression in bacterial cells†‡

Aya Shibata,a   Yoshihiro Ito*a  and  Hiroshi Abe*ab  

* Corresponding authors

a Nano Medical Engineering Laboratory, Advance Science Institute, RIKEN, 2-1, Hirosawa, Wako, Saitama, Japan
E-mail: h-abe@riken.jp, y-ito@riken.jp

b PRESTO, Japan Science and Technology Agency, 4-1-8, Honcho, Kawaguchi, Saitama, Japan

Abstract

We have developed a system to release a biologically active molecule in response to the sequence of a target gene. The releasing system, which was triggered by the reduction of an azidomethyl group, was successfully applied to protein expression induced by the release of IPTG triggered by endogenous RNA in bacterial cells.

Graphical abstract: RNA-templated molecule release induced protein expression in bacterial cells

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Article information

DOI
https://doi.org/10.1039/C2CC37826D
Article type
Communication
Submitted
29 Oct 2012
Accepted
13 Nov 2012
First published
13 Nov 2012

Chem. Commun., 2013,49, 270-272

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RNA-templated molecule release induced protein expression in bacterial cells

A. Shibata, Y. Ito and H. Abe, Chem. Commun., 2013, 49, 270 DOI: 10.1039/C2CC37826D

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