Themed collection Cucurbiturils and related cavitands
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Glycoluril derived cucurbituril analogues and the emergence of the most recent example: tiarauril
Cucurbituril analogues can bear some of the chemical and physical characteristics of their parental origin and are derived wholly or in part from glycolurils (including homologues).
Chem. Commun., 2020,56, 2529-2537
https://doi.org/10.1039/C9CC07233K
Modelling haemoproteins: porphyrins and cyclodextrins as sources of inspiration
Associations of hydrophobic cavities with porphyrin derivatives used to mimic haemoprotein structures are featured in this article and may inspire innovative research in the field of cucurbiturils.
Chem. Commun., 2019,55, 14558-14565
https://doi.org/10.1039/C9CC07545C
Cucurbit[n]uril-based amphiphiles that self-assemble into functional nanomaterials for therapeutics
In this feature article, the two types (molecular amphiphile and supramolecular amphiphile) of CB-based amphiphiles, their self-assemblies and their applications for useful nanotherapeutics and theranostics are presented with future perspectives.
Chem. Commun., 2019,55, 10654-10664
https://doi.org/10.1039/C9CC05567C
Supra-blot: an accurate and reliable assay for detecting target proteins with a synthetic host molecule–enzyme hybrid
A new way to detect target proteins is developed using a high-affinity host–guest interaction for a wide variety of biological samples including bacteria and mammalian cells.
Chem. Commun., 2020,56, 1549-1552
https://doi.org/10.1039/C9CC09699J
Engineered assembly of a protein–cucurbituril biohybrid
Additional Q7 binding sites drive protein aggregation in solution and statistical disorder in the crystalline biohybrid suggest new possibilities for protein-based materials.
Chem. Commun., 2020,56, 360-363
https://doi.org/10.1039/C9CC07198A
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Supramolecular chirogenesis in zinc porphyrins by enantiopure hemicucurbit[n]urils (n = 6, 8)
Chiral cyclohexanohemicucurbit[n]urils with multiple interaction sites induce chirality on planar zinc porphyrins and bind up to three porphyrin molecules.
Chem. Commun., 2019,55, 14434-14437
https://doi.org/10.1039/C9CC07150D
Dynamic host–guest interaction enables autonomous single molecule blinking and super-resolution imaging
Specific yet dynamic interaction in cucurbit[7]uril (CB[7]) system was used to obtain programmable fluorescence blinking with necessary brightness and frequency to enable two-dimensional (2D) and 3D super-resolution imaging of proteins in cells.
Chem. Commun., 2019,55, 14430-14433
https://doi.org/10.1039/C9CC07153A
Outer surface interactions to drive cucurbit[8]uril-based supramolecular frameworks: possible application in gold recovery
Q[8]-based honeycomb-like frameworks could be obtained in [AuCl4]− free aqueous HNO3 solution, aqueous HCl and HNO3 solutions that contain [AuCl4]−. These frameworks exhibit a high selectivity for imprisoning [AuCl4]−.
Chem. Commun., 2019,55, 14271-14274
https://doi.org/10.1039/C9CC07147D
Cooperative enhancement of antibacterial activity of sanguinarine drug through p-sulfonatocalix[6]arene functionalized silver nanoparticles
The amelioration of antibacterial efficacy along with the reduced minimum inhibitory concentration (MIC) of sanguinarine (SGR) drug have been demonstrated through the uptake of SGR by p-sulfonatocalix[6]arene functionalized silver nanoparticles.
Chem. Commun., 2019,55, 14275-14278
https://doi.org/10.1039/C9CC07378G
pH clock instructed transient supramolecular peptide amphiphile and its vesicular assembly
A pH clock directed transient supramolecular peptide amphiphile and its vesicular assembly using ternary complexation of cucurbit[8]uril is displayed.
Chem. Commun., 2019,55, 14119-14122
https://doi.org/10.1039/C9CC06934H
Cucurbit[7]uril promoted Fenton oxidation by modulating the redox property of catalysts
The redox property of a ferrocene derivative is modulated by cucurbit[7]uril, thus accelerating the catalytic oxidation of dye chromophores.
Chem. Commun., 2019,55, 14127-14130
https://doi.org/10.1039/C9CC06877E
A supramolecular five-component relay switch that exposes the mechanistic competition of dissociative versus associative binding to cucurbiturils by ratiometric fluorescence monitoring
A putrescine derivative of aminomethyladamantane is established as a ditopic guest with two mutually exclusive binding sites for cucurbit[6]uril and cucurbit[7]uril.
Chem. Commun., 2019,55, 14123-14126
https://doi.org/10.1039/C9CC07165B
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Binding affinities of cucurbit[n]urils with cations
High binding constants of 19 inorganic cations with the cucurbit[n]uril homologues (CBn, n = 5, 6, 7, 8) in water were determined and the far-reaching consequences and interferences of the high affinities (millimolar to micromolar) are discussed.
Chem. Commun., 2019,55, 14131-14134
https://doi.org/10.1039/C9CC07687E
Mesoporous silica nanobeans dual-functionalized with AIEgens and leaning pillar[6]arene-based supramolecular switches for imaging and stimuli-responsive drug release
Dual-functionalized mesoporous silica nanobeans capable of GSH-dependent turn-on fluorescence and stimuli-responsive drug release are prepared for tumor inhibition and imaging.
Chem. Commun., 2019,55, 14099-14102
https://doi.org/10.1039/C9CC07115F
A single-crystal-to-single-crystal transformation affording photochromic 3D MORF crystals
Metal–organic framework (MOF) type crystals in which rigid, viologen-based pillars are surrounded by cucurbit[7]uril (CB[7]) macrocycles are described.
Chem. Commun., 2019,55, 13824-13827
https://doi.org/10.1039/C9CC07121K
N-Doped holey carbon materials derived from a metal-free macrocycle cucurbit[6]uril assembly as an efficient electrocatalyst for the oxygen reduction reaction
The first example of the preparation of nitrogen-doped holey carbon (NHC) with abundant in-plane holes derived from a rigid macrocycle cucurbit[6]uril self-assembly is reported.
Chem. Commun., 2019,55, 13832-13835
https://doi.org/10.1039/C9CC06939A
Cucurbit[8]uril-based supramolecular nanocapsules with a multienzyme-cascade antioxidative effect
Supramolecular nanocapsules with both SOD and GPx activities were constructed by the ternary host–guest complexation of azobenzene (Azo) and methylviologen (MV) to cucurbit[8]uril (CB[8]) and the subsequent self-assembly.
Chem. Commun., 2019,55, 13820-13823
https://doi.org/10.1039/C9CC07085K
Unveiling the formation 1 : 2 supramolecular complexes between cucurbit[7]uril and a cationic calix[4]arene derivative
The formation of host–guest complexes between cucurbit[7]uril (CB7) and a tetracationic calix[4]arene derivative in the so-called cone conformation was investigated by 1H NMR, DOSY NMR, isothermal titration calorimetry and ESI-MS.
Chem. Commun., 2019,55, 13828-13831
https://doi.org/10.1039/C9CC07280B
Gold nanorods with a noncovalently tailorable surface for multi-modality image-guided chemo-photothermal cancer therapy
Cucurbit[7]uril functionalized Au nanorods allowed noncovalently tailorable surface modification for image-guided, targeted chemo-photothermal cancer therapy in vitro and in vivo.
Chem. Commun., 2019,55, 13506-13509
https://doi.org/10.1039/C9CC07131H
Cucurbit[8]uril-mediated pseudo[2,3]rotaxanes
Cucurbit[8]uril-mediated pseudo[2,3]rotaxanes constrain chromophores into dimeric stacks with effective electron-delocalisation along the long-molecular axis.
Chem. Commun., 2019,55, 13227-13230
https://doi.org/10.1039/C9CC07144J
High affinity threading of a new tetralactam macrocycle in water by fluorescent deep-red and near-infrared squaraine dyes
Guest back-folding increases squaraine affinity for a new tetralactam macrocycle 370-fold in water.
Chem. Commun., 2019,55, 12793-12796
https://doi.org/10.1039/C9CC05244E
Templating conformations with cucurbiturils
The trans- and cis conformations of 5,5′-substituted 2,2′-dithiophenes can be stabilized when those are secured with two Cucurbit[8]uril macrocycles (CB[8]) on top of rigid 2,6- and 2,7-substituted naphthalenes, which respectively mimic the trans and cis conformations of the dithiophene.
Chem. Commun., 2019,55, 12160-12163
https://doi.org/10.1039/C9CC06766C
Decamethylcucurbit[5]uril based supramolecular assemblies as efficient electrocatalysts for the oxygen reduction reaction
A series of decamethylcucurbit[5]uril based supramolecular assemblies were successfully synthesized and explored as efficient electrocatalysts towards the oxygen reduction reaction.
Chem. Commun., 2019,55, 11687-11690
https://doi.org/10.1039/C9CC05899K
Reversible hydrogel dynamics by physical–chemical crosslink photoswitching using a supramolecular macrocycle template
Host–guest supramolecular hydrogels are prepared from light-responsive guests within a CB[8] cavitand, and the complex catalyzes reversible guest photodimerization.
Chem. Commun., 2019,55, 9931-9934
https://doi.org/10.1039/C9CC04748D
Ratiometric DNA sensing with a host–guest FRET pair
A host–guest FRET pair based on a carboxyfluorescein-labelled cucurbit[7]uril and DAPI was developed to sense DNA ratiometrically.
Chem. Commun., 2019,55, 671-674
https://doi.org/10.1039/C8CC09126A