Themed collection Optical Biosensor Devices

The unique optical properties of UCNPs, in particular the ability for background-free optical detection, bestow great potential for food safety and quality monitoring.

Using light as an external stimulus plays a key role not only in modulating activities of nanozymes, but also in constructing efficient biosensing systems.

Multiplexed detections based on optical nanomaterials.

This minireview highlights the developments in optical chemosensors from 2014 to 2016 that utilise the boronic acid interaction with polyols or Lewis bases.

In this mini review, we will provide a brief introduction focusing on the current applications of single plasmonic nanoparticle-based sensors using DFM, including the detection of molecules, the real-time monitoring of chemical/electrochemical reactions and the imaging of living cells.

Recent advances of plasmonic nanoparticle-based optical detection systems for various analytes in homogeneous solution and at the single-nanoparticle level are summarized.

Catalytic properties of gold nanoparticles in colour dye degradation are utilized to amplify colorimetric detection signals of a low-cost paper-based immunosensor for instrument-free detection of pancreatic cancer biomarker PEAK1.

Immunochemical detection of Mozzarella di Bufala Campana and Feta cheese adulteration with cow milk using integrated silicon Mach–Zehnder interferometers.

Here, aggregation-induced emission and quenching were incorporated for the first time in ionophore-based optical nanosensors.

A widefield FD-FLIM system with fast acquisition speed is utilized to accurately characterize oxygen gradient distributions within microfluidic devices.

A novel 1-oxo-1H-phenalene-2,3-dicarbonitrile (OPD)-based fluorescent probe was developed to sense and image GSH in HeLa cells, different imatinib-resistant K562 cells, D. magna and zebrafish embryos.

In this study, sulfur–nitrogen co-doped carbon nanoribbon (SNCNR) polymers with stable dual-emission fluorescence were synthesized using a one-step traditional hydrothermal method of 6-mercaptopurine in an aqueous methanol solution.

In this study, we report the dual detection of kanamycin (KMY) and oxytetracycline (OTC) using metal polydopamine frameworks (MPDA) for the first time.

An aptamer based liquid crystal biosensor was firstly developed for sulfadimethoxine detection achieving a lower detection limit of 10 μg L⁻¹.

Depicting fluorescence sensing of protamine and heparin based on aggregation and disaggregation of copper nanoclusters.

Black phosphorus nanosheets (BPNS) were synthesized from BP crystals through liquid exfoliation coupled with ultrasonic methods under aqueous conditions.

A facile Fe-doped carbon quantum dot based fluorescent sensor for dopamine sensing and bioimaging was constructed.

Herein, we developed a sensitive graphitic carbon nitride quantum dot (gCNQD)-based fluorescent strategy for β-amyloid peptide monomer (Aβ) determination down to the ng mL⁻¹ level for the first time.

A fluorescent molecular probe for assaying BChE activity based on thiol-triggered fluorescence enhancement via a thiol–ene click reaction was developed.

Upon the addition of tyrosinase to the probe solution, the monophenolic unit is oxidized to o-dihydroxy and consequently releases the 4-aminonaphthalimide unit.

A fluorescent sensor based on aggregation-induced emission for amines was prepared and its highly sensitive detection of hydrazine and application in living cell imaging were investigated in detail.

The crucial role of biothiols in many biological processes, which turns them into important biomarkers for the early diagnosis of various diseases, the development of an affordable, sensitive and portable probe for the detection and discrimination of these compounds is of great importance.

A simple and facile strategy is developed for the selective and sensitive detection of dopamine, using luminescent MoS₂ nanohybrid particles.

Hydrogen sulfide (H₂S) and biothiol molecules, such as glutathione (GSH), cysteine (Cys), and homocysteine (Hcy), play an important role in biology.

A new water soluble and fluorogenic probe (L) that can demonstrate the specific ratiometric detection of a SO₂ derivative (SO₃²⁻) in 100% aqueous medium and live cells has been designed and synthesized.

A functionalized gold nanoparticle-enhanced competitive assay was developed to overcome the sensitivity challenge associated with direct SPR sensing of small-molecule metabolites.

Functional CuO/Pt nanocomposites were successfully constructed as peroxidase mimics for highly selective colorimetric detection of ascorbic acid.

An ultrasensitive electrochemiluminescence (ECL) immunosensor for carbohydrate antigen 19-9 (CA19-9) detection using multi-walled carbon nanotube–platinum–luminol nanocomposites (MWCNT–Pt–luminol) as nanointerface and signal tags was designed.