Themed collection Analyst HOT Articles 2022
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Recent progress in electrochemiluminescence microscopy analysis of single cells
An overview of recent progress in electrochemiluminescence microscopy analysis of single cells classified according to different ECL routes, namely the oxidative-reduction, low oxidation potential, catalytic and direct oxidation routes.
Analyst, 2022,147, 2884-2894
https://doi.org/10.1039/D2AN00709F
Recent advances in spheroid-based microfluidic models to mimic the tumour microenvironment
Microfluidic platforms with 3D tumour spheroid culture provide platforms to study the multi-cellular interactions and external stimuli in the complex tumour microenvironment.
Analyst, 2022,147, 2023-2034
https://doi.org/10.1039/D2AN00172A
![Open Access](https://www.rsc-cdn.org/pubs-core/2022.0.147/content/NewImages/open-access-icon-orange.png)
Practical considerations for quantitative and reproducible measurements with stimulated Raman scattering microscopy
This tutorial review presents the most important practical considerations for sample preparation, instrument set-up, image acquisition and data analysis to obtain reproducible SRS measurements.
Analyst, 2022,147, 4642-4656
https://doi.org/10.1039/D2AN00817C
![Open Access](https://www.rsc-cdn.org/pubs-core/2022.0.147/content/NewImages/open-access-icon-orange.png)
Recent advances in antibiotic resistance diagnosis using SERS: focus on the “Big 5” challenges
SERS for antibiotic resistance diagnosis.
Analyst, 2022,147, 4674-4700
https://doi.org/10.1039/D2AN00703G
When AIE meets enzymes
Applications of AIEgens in biosensing, disease diagnosis, and drug release.
Analyst, 2022,147, 3958-3973
https://doi.org/10.1039/D2AN00679K
Use of MALDI-TOF mass spectrometry for virus identification: a review
The possibilities of virus identification, including SARS-CoV-2, by MALDI-TOF mass spectrometry are discussed in this review.
Analyst, 2022,147, 3131-3154
https://doi.org/10.1039/D2AN00431C
Metabolomics-based mass spectrometry methods to analyze the chemical content of 3D organoid models
Mass spectrometry-based metabolomics approaches to characterize the complex intracellular chemistry of organoids are reviewed, expanding the field of organoid research.
Analyst, 2022,147, 2918-2929
https://doi.org/10.1039/D2AN00599A
![Open Access](https://www.rsc-cdn.org/pubs-core/2022.0.147/content/NewImages/open-access-icon-orange.png)
Microfluidic flow cytometry for blood-based biomarker analysis
This review summarises the recent major developments of the key subsystems for microfluidic flow cytometry and its achievements in blood-based biomarker analysis.
Analyst, 2022,147, 2895-2917
https://doi.org/10.1039/D2AN00283C
Biorecognition antifouling coatings in complex biological fluids: a review of functionalization aspects
Recent progress in biointerface research has highlighted the role of antifouling functionalizable coatings in the development of advanced biosensors for point-of-care applications dealing with real-world complex samples.
Analyst, 2022,147, 2597-2614
https://doi.org/10.1039/D2AN00436D
Tandem-trapped ion mobility spectrometry/mass spectrometry (tTIMS/MS): a promising analytical method for investigating heterogenous samples
This review focuses on the instrumental development and potential applications of Tandem-Trapped Ion Mobility Spectrometry/Mass Spectrometry (tTIMS/MS) for protein structure elucidation.
Analyst, 2022,147, 2317-2337
https://doi.org/10.1039/D2AN00335J
“Writing biochips”: high-resolution droplet-to-droplet manufacturing of analytical platforms
Depletion-free molecular ink deposition with accurate volume control allows for the fabrication of droplet-based bioanalytical assays.
Analyst, 2022,147, 1294-1312
https://doi.org/10.1039/D1AN02295D
Paving the way towards continuous biosensing by implementing affinity-based nanoswitches on state-dependent readout platforms
Combining affinity-based nanoswitches with state-dependent readout platforms allows for continuous biosensing and acquisition of real-time information about biochemical processes occurring in the environment of interest.
Analyst, 2022,147, 1006-1023
https://doi.org/10.1039/D1AN02308J
Recent progress in the development of porous carbon-based electrodes for sensing applications
Electrochemical (bio)sensors are considered clean and powerful analytical tools capable of converting an electrochemical reaction between analytes and electrodes into a quantitative signal.
Analyst, 2022,147, 767-783
https://doi.org/10.1039/D1AN01978C
Hyperpolarized 29Si magnetic resonance spectroscopy of selectively radical-embedded silica nanoparticles
Homogeneously radical-grafted SiO2 NPs were effectively self-polarized and represented enhanced 29Si signal amplification via DNP.
Analyst, 2022,147, 5607-5612
https://doi.org/10.1039/D2AN01684B
Ultra-thin silica shell-guarded nanoflares for high-fidelity live cell miRNA-21 imaging by fully avoiding the interference of biothiols
Ultra-thin silica-guarded nanoflares (Au@SiO2 NFs) are constructed for high-fidelity live cell microRNA imaging by avoiding the interference of intracellular biothiols.
Analyst, 2022,147, 5269-5273
https://doi.org/10.1039/D2AN01441F
A bioluminescent probe for NQO1 overexpressing cancer cell imaging in vitro and in vivo
A bioluminescent probe NQO1-Luc toward NQO1 was constructed, which exhibits high selectivity and sensitivity toward NQO1 in vitro and adequate capability of distinguishing NQO1-overexpressing tumors in vivo.
Analyst, 2022,147, 5264-5268
https://doi.org/10.1039/D2AN01435A
A lysosome-targeting fluorescent probe to visualize endogenous and exogenous methylglyoxal in live cells and zebrafish
The first fluorescent probe targeting MGO in lysosomes was developed for the detection of intracellular and extracellular sources of methylglyoxal.
Analyst, 2022,147, 4949-4953
https://doi.org/10.1039/D2AN01386J
Nitric acid concentration strongly influences low level uranium determination on PEDOT-PSS coated glassy carbon electrodes
Nitric acid concentration plays an important role in quantifying very low levels of uranium on PEDOT-PSS/GC electrodes. Its lower acidity (0.05 M) favours free UO22+ which complexes with PEDOT-PSS and thereby increases the detection limit.
Analyst, 2022,147, 4724-4729
https://doi.org/10.1039/D2AN01390H
Aptamer-engineered extended-gate field-effect transistor device for point-of-care therapeutic drug monitoring
A portable point-of-care testing (POCT) device based on an aptamer-engineered extended-gate field-effect transistor (EG-FET) was unveiled for therapeutic monitoring of the drug methotrexate.
Analyst, 2022,147, 4413-4416
https://doi.org/10.1039/D2AN01393B
Spatially-extended 3D magnetic DNA nanodevice-based split-type photoelectrochemical strategy for sensitive and reliable miRNA detection in cancer cells
To improve the accuracy of PEC sensing. We developed a split-type “turn-off” PEC biosensor based on spatially-extended 3D magnetic DNA nanodevices with high-order DNA amplifiers for sensitive and reliable detection of miRNAs in cancer cells.
Analyst, 2022,147, 3415-3419
https://doi.org/10.1039/D2AN00712F
Single-particle spectroelectrochemistry: electrochemical tuning of plasmonic properties via mercury amalgamation in mesoporous silica coated gold nanorods without structural deformation
This paper presented the possibility of the in situ tuning of the LSPR properties of AuNRs@mSiO2 by Hg deposition via electrochemical potential manipulations without the disturbance of the structural variations of AuNR cores.
Analyst, 2022,147, 2035-2039
https://doi.org/10.1039/D2AN00559J
A PEGylated water-soluble fluorescent and colorimetric probe for carbon monoxide detection
A PEGylated water-soluble CO probe is synthesized, achieving the detection of CO with high intensity color change and fluorescence enhancement.
Analyst, 2022,147, 1798-1802
https://doi.org/10.1039/D2AN00118G
Oxytocin detection at ppt level in human saliva by an extended-gate-type organic field-effect transistor
An extended-gate-type organic field-effect transistor immunosensor has successfully detected oxytocin at ppt levels in human saliva with high recovery rates (96–102%).
Analyst, 2022,147, 1055-1059
https://doi.org/10.1039/D1AN02188E
Leveraging mid-infrared spectroscopic imaging and deep learning for tissue subtype classification in ovarian cancer
This study introduces label-free, automated ovarian tissue cell recognition using O-PTIR imaging, offering 10× better resolution than FTIR. It outperforms FTIR, achieving 0.98 classification accuracy. This work aids early ovarian cancer diagnosis.
Analyst, 2023,148, 2699-2708
https://doi.org/10.1039/D2AN01035F
Sulfur and nitrogen served as electron donors to rescue short wave emission or fluorescence quenching caused by nucleophilic addition
SO2 is not only a new potential gas signaling molecule, but also an antioxidant and antioxidant metabolite, which plays an important role in biophysiological and pathological processes.
Analyst, 2022,147, 5663-5669
https://doi.org/10.1039/D2AN01794F
Chemiluminescence resonance energy transfer as a simple and sensitive readout mode for a CRISPR/Cas12a-based biosensing platform
In this CRET readout, the CL reaction of TCPO–H2O2 was used to replace the exciting light source of the FRET readout, which makes the instrument simpler and easier to miniaturize.
Analyst, 2022,147, 5687-5693
https://doi.org/10.1039/D2AN01735K
Synthesis and characterization of a biocompatible 13C1 isotopologue of trityl radical OX071 for in vivo EPR viscometry
We report an isotopologue of the trityl radical OX071, labeled with 13C at the central carbon highly sensitive to molecular tumbling.
Analyst, 2022,147, 5643-5648
https://doi.org/10.1039/D2AN01527G
Glucose oxidase-encapsulated liposomes for amplified autofluorescence-free immunoassay of a prostate-specific antigen with photoluminescence of CePO4:Tb nanocrystals
An autofluorescence-free immunosensing platform was designed to determine prostate-specific antigen based on the photoluminescence of CePO4:Tb nanocrystals.
Analyst, 2022,147, 5680-5686
https://doi.org/10.1039/D2AN01689C
Floating Ag-NPs@Cu-NW bundles fabricated on copper mesh for highly sensitive SERS detection of uric acid in pretreatment-free urine
Bundle-like structures decorated with Ag nanoparticles can be used as active floating SERS substrates with abundant 3D hot spots for highly sensitive detection of uric acid based on capillary forces that drive target molecules into the hot spots.
Analyst, 2022,147, 5670-5679
https://doi.org/10.1039/D2AN01586B
Specific detection of fusion transcripts based on a duplex-specific nuclease and isothermal exponential amplification reaction
A DSN-IEXPAR method is developed for the specific detection of fusion transcripts.
Analyst, 2022,147, 5649-5654
https://doi.org/10.1039/D2AN01665F
A novel electrochemical sensor based on AuPd/UiO-66-NH2/GN composites for sensitive dopamine detection
The AuPd/UiO-66-NH2/GN composites were successfully synthesized. And they were used to modify a glassy carbon electrode to construct a novel electrochemical sensor for sensitive dopamine detection.
Analyst, 2022,147, 5655-5662
https://doi.org/10.1039/D2AN01538B
A signal on–off strategy based on the digestion of DNA cubes assisted by the CRISPR–Cas12a system for ultrasensitive HBV detection in solid-state nanopores
A sensing strategy for the ultrasensitive detection of HBV in nanopores was constructed by digestion of elements of DNA cubes and the use of CRISPR–Cas12a technology. Coupling with PCR preamplification technology enabled HBV-positive or -negative classification.
Analyst, 2022,147, 5623-5632
https://doi.org/10.1039/D2AN01402E
Selective non-enzymatic uric acid sensing in the presence of dopamine: electropolymerized poly-pyrrole modified with a reduced graphene oxide/PEDOT:PSS composite
A molecularly imprinted polymer (MIP) with uric acid cavities increases the selectivity of uric acid measurement in the presence of dopamine as an interferent.
Analyst, 2022,147, 5334-5346
https://doi.org/10.1039/D2AN01463G
Development of a PNA–DiSc2 based portable absorbance platform for the detection of pathogen nucleic acids
A PortAbs based pathogen nucleic acid detection system using peptide nucleic acid (PNA) and a cyanine dye, DiSc2(5). The shift is measured of the absorbance induced by binding of a PNA probe to a complementary DNA strand using a portable two-color absorption system.
Analyst, 2022,147, 5306-5313
https://doi.org/10.1039/D2AN01351G
Microplasma-assisted synthesis of a mixed-valence Ce-MOF with enhanced oxidase-like activity for colorimetric sensing of dopamine
Mixed valence Ce-MOF (MVCM) with enhanced cataltical activity was synthesized by dielectric barrier discharge (DBD) microplasma, and a colorimetric platform of oxidase-like MVCM was established for DA detection.
Analyst, 2022,147, 5355-5362
https://doi.org/10.1039/D2AN01420C
![Open Access](https://www.rsc-cdn.org/pubs-core/2022.0.147/content/NewImages/open-access-icon-orange.png)
Quantification anomalies in single pulse LA-ICP-MS analysis associated with laser fluence and beam size
Laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) has undergone major improvements in recent years which have led to reduction of the analysis time, higher spatial resolution, and better sensitivity.
Analyst, 2022,147, 5293-5299
https://doi.org/10.1039/D2AN01172G
Cu(II)-assisted self-assembly of dicyandiamide-derived carbon dots: construction inspired from chemical evolution and its H2O2 sensing application
In the rapid development of artificial nanomaterials comparable to biological enzymes, we propose herein a novel concept for the construction of functional materials inspired from chemical evolution.
Analyst, 2022,147, 5324-5333
https://doi.org/10.1039/D2AN01232D
A robust colorimetric aptasensor for the label-free detection of marine toxins based on tyrosine-capped gold nanoparticles
Tyrosine-capped AuNPs decrease the interaction between targets and AuNPs, presenting better robustness than traditional Cit-AuNPs. Utilizing the superior features, a label-free aptasensor is developed for marine toxin detection for the first time.
Analyst, 2022,147, 5314-5323
https://doi.org/10.1039/D2AN01394K
Chlorination-induced pKa decrease: an improved strategy to design ratiometric hypochlorite fluorescent probes with ideally high selectivity
Based on the ClO−-triggered chlorination reaction and the subsequent pKa decrease, a two-photon ratiometric ClO− fluorescent probe was designed.
Analyst, 2022,147, 5300-5305
https://doi.org/10.1039/D2AN01476A
A microbial quantity monitoring model based on 3D fluorescence data of the cucumber storeroom gas and its use in providing auxiliary early spoilage warning
A microbial quality prediction model for early warning of cucumber spoilage is proposed based on the fluorescence information of the cucumber storeroom gas.
Analyst, 2022,147, 5347-5354
https://doi.org/10.1039/D2AN01121B
Electrochemically functionalized graphene for highly sensitive detection of nitrofurazone
The electrochemically functionalized graphene nanosheets (EGS) possesses more oxygen-containing groups and higher defect level, showing superior electrochemical sensing performance.
Analyst, 2022,147, 5011-5017
https://doi.org/10.1039/D2AN01428A
Phosphorothioated and phosphate-terminal dumbbell (PP-TD) probe-based rapid detection of polynucleotide kinase activity
A primer-free, sensitive assay has been developed to detect polynucleotide kinase (PNK) activity. This proposed method provides a promising platform for PNK activity monitoring and inhibition screening for drug discovery and clinical treatment.
Analyst, 2022,147, 4986-4990
https://doi.org/10.1039/D2AN01431A
Ultrasensitive detection of DNA methyltransferase activity: a novel dual-amplification fluorescence technique
A dual amplification fluorescence strategy was developed for the ultrasensitive detection of Dam MTase activity based on strand displacement amplification coupled with rolling circle amplification.
Analyst, 2022,147, 4980-4985
https://doi.org/10.1039/D2AN01302A
Rapid and sensitive SARS-CoV-2 detection using a homogeneous fluorescent immunosensor Quenchbody with crowding agents
A Quenchbody immunosensor for SARS-CoV-2 nucleocapsid protein was developed, and 5% PEG6000 significantly improved its response speed and sensitivity. Positive and negative groups of COVID-19 clinical samples were distinguished.
Analyst, 2022,147, 4971-4979
https://doi.org/10.1039/D2AN01051H
Structural elucidation and isomeric differentiation/quantitation of monophosphorylated phosphoinositides using gas-phase ion/ion reactions and dissociation kinetics
Monophosphorylated phosphoinositides doubly deprotonated ions are subjected to sequential gas-phase ion/ion reactions. By utilizing ion/ion reaction products and performing kinetic experiments, dissociation rates are retrieved.
Analyst, 2022,147, 5000-5010
https://doi.org/10.1039/D2AN00792D
High-throughput and directed microparticle manipulation in complex-shaped maze chambers based on travelling surface acoustic waves
A novel traveling surface acoustic wave (TSAW)-based manipulation device that allows for automated and high-throughput maze-solving manipulation of microparticles inside complex round-shaped and square-shaped maze chambers.
Analyst, 2022,147, 4962-4970
https://doi.org/10.1039/D2AN01317G
Superior performance of a graphdiyne self-powered biosensor with exonuclease III-assisted signal amplification for sensitive detection of microRNAs
Graphdiyne couples with an exonuclease III-assisted amplification strategy to construct a superior-performance self-powered biosensor based on enzymatic biofuel cells for highly sensitive detection of the tumour marker miRNA-21.
Analyst, 2022,147, 4991-4999
https://doi.org/10.1039/D2AN01384C
Stress induced self-rollable smart-stent-based U-health platform for in-stent restenosis monitoring
To date, several smart stents have been proposed to continuously detect biological cues, which is essential for tracking patients’ critical vital signs and therapy.
Analyst, 2022,147, 4793-4803
https://doi.org/10.1039/D2AN01258H
An automatic whole blood analyzer for renal function analysis with a centrifugal microfluidic device
The centrifugal microfluidic system for whole blood creatinine detection.
Analyst, 2022,147, 4804-4814
https://doi.org/10.1039/D2AN01218A
A deep clustering-based mass spectral data visualization strategy for anti-renal fibrotic lead compound identification from natural products
We present a deep clustering-based MS data visualization strategy (MCnebula), integrated with the influential open-source automatic MS annotation platform SIRIUS and in vivo and in vitro methods, to screen and validate potential lead compounds from natural products.
Analyst, 2022,147, 4739-4751
https://doi.org/10.1039/D2AN01185A
Novel ratiometric electrochemical sensing platform for uric acid based on electroactive cuprous oxide nanocubes combined with boron carbide
Electrochemically active oxides play important roles in the fabrication of electrochemical sensing platforms, in which they can be utilized as electrochemical probes or catalysts in electrochemical reactions.
Analyst, 2022,147, 4777-4785
https://doi.org/10.1039/D2AN01270G
One-step and highly sensitive quantification of fusion genes with isothermal amplification initiated by a fusion-site anchored stem-loop primer
A one-step method was developed for the fusion gene assay with high sensitivity and specificity by a fusion-site anchored stem-loop primer to initiate isothermal amplification.
Analyst, 2022,147, 4786-4792
https://doi.org/10.1039/D2AN01300B
Electrochemiluminescence biosensor for cardiac troponin I with signal amplification based on a MoS2@Cu2O–Ag-modified electrode and Ce:ZnO-NGQDs
A sensitive sandwiched electrochemiluminescence (ECL) immunosensor was built for the detection of cTnI. The ECL immunosensor had a low detection limit (2.90 fg mL−1) and wide detection range (10 pg mL−1 to 100 ng mL−1).
Analyst, 2022,147, 4768-4776
https://doi.org/10.1039/D2AN01341J
PBA-MoS2 nanoboxes with enhanced peroxidase activity for constructing a colorimetric sensor array for reducing substances containing the catechol structure
A fast colorimetric sensor array is constructed based on the enhanced peroxidase-like activity of nickel cobalt Prussian blue analogue-MoS2 nanoboxes (PBA-MoS2) for the detection of reducing substances containing the catechol structure.
Analyst, 2022,147, 4761-4767
https://doi.org/10.1039/D2AN01211A
Ion-selective electrode-based potentiometric immunoassays for the quantitative monitoring of alpha-fetoprotein by coupling rolling cycle amplification with silver nanoclusters
This work reports an ion-selective electrode-based potentiometric immunoassay for AFP detection coupling rolling cycle amplification with silver nanoclusters.
Analyst, 2022,147, 4752-4760
https://doi.org/10.1039/D2AN01282K
Positive feedback drives a secondary nonlinear product burst during a biphasic DNA amplification reaction
Ultrasensitive DNA Amplification Reaction (UDAR) provides a unique biphasic fluorescence output derived from a second phase switch-like burst in reaction products. We quantified the two main reaction products and present a mathematical model that can reproduce the reaction output, including the nonlinear autocatalytic product burst in the second phase.
Analyst, 2022,147, 4450-4461
https://doi.org/10.1039/D2AN01067D
A rapid and simple electrochemical detection of the free drug concentration in human serum using boron-doped diamond electrodes
Monitoring drug concentration in blood and reflecting this in the dosage are crucial for safe and effective drug treatment.
Analyst, 2022,147, 4442-4449
https://doi.org/10.1039/D2AN01037B
Serum fingerprinting by slippery liquid-infused porous SERS for non-invasive lung cancer detection
Direct and label-free analysis of clinical serum samples using slippery liquid-infused porous-enhanced Raman spectroscopy (SLIPSERS) enables the rapid non-invasive identification of lung cancer.
Analyst, 2022,147, 4426-4432
https://doi.org/10.1039/D2AN01325H
Reusable and universal impedimetric sensing platform for the rapid and sensitive detection of pathogenic bacteria based on bacteria-imprinted polythiophene film
A bacteria-imprinted polythiophene film (BIF)-based impedimetric sensor was proposed for the rapid and sensitive detection of S. aureus. A significant improvement is the reduced time for both BIF fabrication (15 min) and bacterial capturing (10 min).
Analyst, 2022,147, 4433-4441
https://doi.org/10.1039/D2AN01122K
A benzimidazole-based ratiometric fluorescent probe for the accurate and rapid monitoring of lysosomal pH in cell autophagy and anticounterfeiting
The lysosomal targeted ratiometric fluorescent BD probe reveals excellent application performance in the fields of selective monitoring of the lysosome pH of living cells, real-time dynamic monitoring of autophagy, and document anti-counterfeiting.
Analyst, 2022,147, 4389-4398
https://doi.org/10.1039/D2AN01112C
Efficient exosome subpopulation isolation and proteomic profiling using a Sub-ExoProfile chip towards cancer diagnosis and treatment
Deconstruction of the heterogeneity of surface marker-dependent exosome subpopulations by the Sub-ExoProfile chip.
Analyst, 2022,147, 4237-4248
https://doi.org/10.1039/D2AN01268E
A handy imaging sensor array based on the phase transformation from CsPbBr3 to CsPb2Br5: highly sensitive and rapid detection of water content in ethanol
This work proposes a handy imaging sensor array based on the phase transformation from CsPbBr3 to CsPb2Br5 for highly sensitive and rapid detection of the water content in ethanol.
Analyst, 2022,147, 4228-4236
https://doi.org/10.1039/D2AN01016J
![Open Access](https://www.rsc-cdn.org/pubs-core/2022.0.147/content/NewImages/open-access-icon-orange.png)
Direct low field J-edited diffusional proton NMR spectroscopic measurement of COVID-19 inflammatory biomarkers in human serum
A JEDI NMR pulse experiment incorporating relaxation, diffusion and J-modulation peak editing was implemented at a low field (80 MHz) spectrometer system to quantify two recently discovered plasma markers of SARS-CoV-2 infection and general inflammation.
Analyst, 2022,147, 4213-4221
https://doi.org/10.1039/D2AN01097F
A tracer-type fluorescent probe for imaging adenosine triphosphate under the stresses of hydrogen sulfide and hydrogen peroxide in living cells
Adenosine triphosphate (ATP) is a direct energy source in cells and the core of the biochemical system, and is closely related to various metabolic activities in living organisms.
Analyst, 2022,147, 4222-4227
https://doi.org/10.1039/D2AN01262F
Construction of a HPLC-SERS hyphenated system for continuous separation and detection based on paper substrates
The HPLC-SERS hyphenated system exhibited the complementary capability of on-line separation and continuous structural identification. It was extended to the application in identifying the illegally added hypoglycemic drugs in the practical dietary supplements.
Analyst, 2022,147, 4073-4081
https://doi.org/10.1039/D2AN00993E
On-chip immunomagnetic separation of allergens from myofibrillar proteins of seafoods for rapid allergy tests
An on-chip strategy to analyze the allergens existing in myofibrillar proteins of seafood matrices using anti-human IgE-functionalized magnetic beads (MBs) has the potential to be applied in blood tests for food allergies with a single drop of blood.
Analyst, 2022,147, 4063-4072
https://doi.org/10.1039/D2AN00813K
Au nanoflower film-based stretchable biosensors for in situ monitoring of superoxide anion release in cell mechanotransduction
Cell mechanotransduction plays an important role in vascular regulation and disease development.
Analyst, 2022,147, 4055-4062
https://doi.org/10.1039/D2AN01095J
Dual-strategy biosensing of glucose based on multifunctional CuWO4 nanoparticles
The multifunctional CuWO4 NPs were prepared and exhibit large specific surface area, good conductivity and excellent peroxidase-like activity, which was exploited for electrochemical and colorimetric dual-strategy biosensing of glucose.
Analyst, 2022,147, 4049-4054
https://doi.org/10.1039/D2AN01003H
![Open Access](https://www.rsc-cdn.org/pubs-core/2022.0.147/content/NewImages/open-access-icon-orange.png)
Time resolved growth of (N)-polycyclic aromatic hydrocarbons in engine deposits uncovered with OrbiSIMS depth profiling
Insoluble carbonaceous deposits were grown in internal combustion engine components and interrogated by OrbiSIMS depth profiling, and we uncovered the composition and proposed time resolved growth mechanisms of these materials.
Analyst, 2022,147, 3854-3866
https://doi.org/10.1039/D2AN00798C
Smartphone clip-on instrument and microfluidic processor for rapid sample-to-answer detection of Zika virus in whole blood using spatial RT-LAMP
Rapid, simple, inexpensive, accurate and sensitive point-of-care (POC) detection of viral pathogens in bodily fluids is a vital component of controlling the spread of infectious diseases.
Analyst, 2022,147, 3838-3853
https://doi.org/10.1039/D2AN00438K
About this collection
This themed collection features articles published in Analyst marked as HOT by the handling editor or as recommended by referees. Congratulations to all the authors whose articles are featured.