γ-Glutamyltranspeptidase and pH based “AND” logic gate fluorescent probe for orthotopic breast tumor imaging

Li-Na Zhang; Hong Zhang; Shan-Yong Chen; Yan-Zhao Liu; Xiao-Hua Yang; Fei-Fan Xiang; Yan-Hong Liu; Kun Li; Xiao-Qi Yu

doi:10.1039/D2CC06568A

You do not have JavaScript enabled. Please enable JavaScript to access the full features of the site or access our non-JavaScript page.

γ-Glutamyltranspeptidase and pH based “AND” logic gate fluorescent probe for orthotopic breast tumor imaging†

Li-Na Zhang,^a Hong Zhang,^a Shan-Yong Chen,

*^a Yan-Zhao Liu,^a Xiao-Hua Yang,^a Fei-Fan Xiang,^a Yan-Hong Liu,^a Kun Li

*^a and Xiao-Qi Yu

^ab

Author affiliations

* Corresponding authors

^a Key Laboratory of Green Chemistry and Technology, Ministry of Education, College of Chemistry, Sichuan University, Chengdu, China
E-mail: chensy@scu.edu.cn, kli@scu.edu.cn

^b Asymmetric Synthesis and Chiral Technology Key Laboratory of Sichuan Province, Department of Chemistry, Xihua University, Chengdu 610039, China

Abstract

An “AND” logic gate-based NIR fluorescent probe Si-NH₂-Glu was developed based on novel meso-amine Si-Rhodamine, which combined γ-glutamyl transpeptidase and pH dual-responsive sites. The features of Si-NH₂-Glu enable it to be applied in orthotopic tumor imaging and fluorescence-guided surgery.

This article is part of the themed collection: Chemosensors and Molecular Logic

Download options Please wait...

Supplementary files

Supplementary information PDF (2377K)

Article information

DOI: https://doi.org/10.1039/D2CC06568A
Article type: Communication
Submitted: 02 déc. 2022
Accepted: 07 févr. 2023
First published: 08 févr. 2023

Download Citation

Chem. Commun., 2023,59, 2795-2798

Permissions

Request permissions

γ-Glutamyltranspeptidase and pH based “AND” logic gate fluorescent probe for orthotopic breast tumor imaging

L. Zhang, H. Zhang, S. Chen, Y. Liu, X. Yang, F. Xiang, Y. Liu, K. Li and X. Yu, Chem. Commun., 2023, 59, 2795 DOI: 10.1039/D2CC06568A

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Social activity

Fetching data from CrossRef.
This may take some time to load.

Chemical Communications

γ-Glutamyltranspeptidase and pH based “AND” logic gate fluorescent probe for orthotopic breast tumor imaging†

Abstract

Supplementary files

Article information

Download Citation

Permissions

γ-Glutamyltranspeptidase and pH based “AND” logic gate fluorescent probe for orthotopic breast tumor imaging

Social activity

Search articles by author

Spotlight

Advertisements