Issue 92, 2022

New cell-membrane-anchored near-infrared fluorescent probes for viscosity monitoring

Abstract

New amphiphilic near-infrared fluorescent probes (λem = 710 nm) are reported for monitoring viscosity of cell membranes. The probes were found to be selective and sensitive to viscosity, and to quickly (within 2 minutes) and stably anchor onto the cell membrane. Moreover, the applicability of the probe MYN-BS (a superior representative) was demonstrated, revealing a reversible viscosity change with temperature change and an increase in viscosity during cell foaming. The proposed probes may serve as a reliable tool for studying viscosity-related processes of cell membranes.

Graphical abstract: New cell-membrane-anchored near-infrared fluorescent probes for viscosity monitoring

Supplementary files

Article information

Article type
Communication
Submitted
30 sept. 2022
Accepted
25 oct. 2022
First published
26 oct. 2022

Chem. Commun., 2022,58, 12815-12818

New cell-membrane-anchored near-infrared fluorescent probes for viscosity monitoring

Y. Liu, X. Li, W. Shi and H. Ma, Chem. Commun., 2022, 58, 12815 DOI: 10.1039/D2CC05362D

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