Issue 20, 2022

Controlled release of drug molecules by pillararene-modified nanosystems

Abstract

Stimuli-responsive nanosystems have attracted the interest of researchers due to their intelligent function of controlled release regulated by a variety of external stimuli and have been applied in biomedical fields. Pillar[n]arenes with the advantages of a rigid structure, electron holes and easy functionalization are considered as excellent candidates for the construction of host–guest nanosystems. In recent years, many pillararene modified nanosystems have been reported in response to different stimuli. In this feature article, we summarize the advance of stimuli-responsive pillararene modified nanosystems for controlled release of drugs from the perspectives of decomposition release and gated release, focusing on the control principles of these nanosystems. We expect that this review can enlighten and guide investigators in the field of stimuli-responsive controlled release.

Graphical abstract: Controlled release of drug molecules by pillararene-modified nanosystems

Article information

Article type
Feature Article
Submitted
03 oct. 2021
Accepted
19 janv. 2022
First published
18 févr. 2022

Chem. Commun., 2022,58, 3255-3269

Controlled release of drug molecules by pillararene-modified nanosystems

Q. Yang, W. Xu, M. Cheng, S. Zhang, E. G. Kovaleva, F. Liang, D. Tian, J. Liu, R. M. Abdelhameed, J. Cheng and H. Li, Chem. Commun., 2022, 58, 3255 DOI: 10.1039/D1CC05584D

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