A soluble iron(II)-phthalocyanine-catalyzed intramolecular C(sp3)–H amination with alkyl azides

Tingjie You; Si-Hao Zeng; Jianqiang Fan; Liangliang Wu; Fangyuan Kang; Yungen Liu; Chi-Ming Che

doi:10.1039/D1CC04573C

You do not have JavaScript enabled. Please enable JavaScript to access the full features of the site or access our non-JavaScript page.

A soluble iron(ii)-phthalocyanine-catalyzed intramolecular C(sp³)–H amination with alkyl azides†

Tingjie You,^ab Si-Hao Zeng,^ac Jianqiang Fan,^a Liangliang Wu,^ab Fangyuan Kang,^a Yungen Liu

*^a and Chi-Ming Che

*^abcde

Author affiliations

* Corresponding authors

^a Department of Chemistry, Southern University of Science and Technology, Shenzhen, Guangdong 518055, P. R. China
E-mail: cmche@hku.hk, liuyg@sustech.edu.cn

^b Department of Chemistry and State Key Laboratory of Synthetic Chemistry, The University of Hong Kong, Hong Kong, P. R. China

^c College of Chemistry, Central China Normal University, Wuhan 430079, P. R. China

^d HKU Shenzhen Institute of Research and Innovation, Shenzhen, Guangdong 518057, P. R. China

^e Laboratory for Synthetic Chemistry and Chemical Biology Limited, Units 1503-1511, 15/F., Building 17W, Hong Kong Science and Technology Parks, New Territories, Hong Kong, P. R. China

Abstract

Herein, we describe a soluble iron(II)-phthalocyanine, [Fe^II(^tBu₄Pc)(py)₂] (Pc = phthalocyaninato(2–)), as an effective catalyst in intramolecular C(sp³)–H bond amination, with alkyl azides as the nitrogen source, to afford the amination products in moderate to excellent yields with a broad substrate scope.

This article is part of the themed collection: Functionalization of unreactive C-H bonds

Download options Please wait...

Supplementary files

Article information

DOI: https://doi.org/10.1039/D1CC04573C
Article type: Communication
Submitted: 18 août 2021
Accepted: 14 sept. 2021
First published: 23 sept. 2021

Download Citation

Chem. Commun., 2021,57, 10711-10714

Permissions

Request permissions

A soluble iron(II)-phthalocyanine-catalyzed intramolecular C(sp³)–H amination with alkyl azides

T. You, S. Zeng, J. Fan, L. Wu, F. Kang, Y. Liu and C. Che, Chem. Commun., 2021, 57, 10711 DOI: 10.1039/D1CC04573C

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Social activity

Fetching data from CrossRef.
This may take some time to load.

Chemical Communications