Issue 4, 2021

Applications of DNA-nanozyme-based sensors

Abstract

Since the discovery of the enzyme-like activities of nanomaterials, the study of nanozymes has become one of the most popular research frontiers of diverse areas including biosensors. DNA also plays a very important role in the construction of biosensors. Thus, the idea of combined applications of nanozymes with DNA (DNA-nanozyme) is very attractive for the development of nanozyme-based biosensors, which has attracted considerable interest of researchers. To date, many sensors based on DNA-functionalized or templated nanozymes have been reported for the detection of various targets and highly accelerated the development of nanozyme-based sensors. In this review, we summarize the main applications and advances of DNA-nanozyme-based sensors. Additionally, perspectives and challenges are also discussed at the end of the review.

Graphical abstract: Applications of DNA-nanozyme-based sensors

Article information

Article type
Tutorial Review
Submitted
10 déc. 2020
Accepted
12 janv. 2021
First published
12 janv. 2021

Analyst, 2021,146, 1127-1141

Applications of DNA-nanozyme-based sensors

R. Yu, R. Wang, Z. Wang, Q. Zhu and Z. Dai, Analyst, 2021, 146, 1127 DOI: 10.1039/D0AN02368J

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