Issue 7, 2019
From the journal:

Organic & Biomolecular Chemistry

Total synthesis of (±)-antroquinonol†

Xiaoming Wang,a   Chao Du,a   Benke Honga  and  Xiaoguang Lei ORCID logo *a  

* Corresponding authors

a Beijing National Laboratory for Molecular Sciences, Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, Department of Chemical Biology, College of Chemistry and Molecular Engineering, Synthetic and Functional Biomolecules Center, and Peking-Tsinghua Center for Life Sciences, Peking University, Beijing 100871, China
E-mail: xglei@pku.edu.cn

Abstract

We report the total synthesis of (±)-antroquinonol based on a concise and efficient route. Key features include two different strategies to install the required three contiguous stereogenic centers, which not only furnish the desired natural product but also provide natural product congeners for further biological studies.

Graphical abstract: Total synthesis of (±)-antroquinonol

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Article information

DOI
https://doi.org/10.1039/C8OB02494D
Article type
Communication
Submitted
08 oct. 2018
Accepted
05 nov. 2018
First published
05 nov. 2018

Org. Biomol. Chem., 2019,17, 1754-1757

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Total synthesis of (±)-antroquinonol

X. Wang, C. Du, B. Hong and X. Lei, Org. Biomol. Chem., 2019, 17, 1754 DOI: 10.1039/C8OB02494D

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